Results 31 to 40 of about 7,259,671 (332)

Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer

open access: yesNature Communications, 2022
Immunoglobulin M (IgM) is the Ig isotype that serves as the first line of host defence during infection. Here, the authors image the full-length IgM pentamer by cryo-EM, revealing the structure and hinge motion of the antigen binding domains.
Qu Chen   +4 more
doaj   +1 more source

Seeing more than we can know: Visual attention and category activation [PDF]

open access: yes, 1999
Extending existing work on the conditional automaticity of category activation, the present research investigated the extent to which category activation is moderated by the resolution of visual attention.
Bodenhausen, GV   +3 more
core   +2 more sources

Dinuclear PhosphoiminoBINOL-Pd Container for Malononitrile: Catalytic Asymmetric Double Mannich Reaction for Chiral 1,3-Diamine Synthesis

open access: yesScientific Reports, 2018
A phosphoiminoBINOL ligand was designed to form a dinuclear metal complex that could hold a malononitrile molecule. The dinuclear bis(phosphoimino)binaphthoxy-Pd2(OAc)2 complex catalyzed a double Mannich reaction of N-Boc-imines with malononitrile to ...
Takayoshi Arai   +4 more
doaj   +1 more source

Voluntary activation of human knee extensors measured using transcranial magnetic stimulation [PDF]

open access: yes, 2009
The aim of this study was to determine the applicability and reliability of a transcranial magnetic stimulation twitch interpolation technique for measuring voluntary activation of a lower limb muscle group.
Goodall, Stuart, Romer, Lee, Ross, Emma
core   +1 more source

Active learning enabled activity recognition [PDF]

open access: yesPervasive and Mobile Computing, 2016
© 2016 IEEE, 2016 IEEE International Conference on Pervasive Computing and Communications (PerCom)
Hossain, H M Sajjad   +2 more
openaire   +1 more source

Interrogating ligand-receptor interactions using highly sensitive cellular biosensors

open access: yesNature Communications, 2023
Interactions of membrane-resident proteins are important targets for therapeutic interventions but most methods to study them are either costly, laborious or fail to reflect the physiologic interaction of membrane resident proteins in trans.
Maximilian A. Funk   +10 more
doaj   +1 more source

Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia. [PDF]

open access: yes, 2014
Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International Licence.
A Castano   +30 more
core   +3 more sources

B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments

open access: yeseLife, 2019
Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto ...
Sophie I Roper   +5 more
doaj   +1 more source

The Impact of Knowledge About Business Model Canvas (BMC) on Entrepreneurial Interest of Young Generation in Jabodetabek

open access: yesIndonesian Journal of Business and Entrepreneurship
This research aims to investigate the influence of Business Model Canvas (BMC) knowledge on entrepreneurial knowledge among young generations in the Jabodetabek region.
Nur Hendrasto   +4 more
doaj   +1 more source

A Mouse Model to Study the Pathogenesis of γ-herpesviral Infections in Germinal Center B Cells

open access: yesCells, 2023
CD30-positive germinal center (GC)-derived B cell lymphomas are frequently linked to Epstein–Barr Virus (EBV) infection. However, a suitable animal model for the investigation of the interplay between γ-herpesvirus and host cells in B cell pathogenesis ...
Ursula Rambold   +8 more
doaj   +1 more source

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