Results 21 to 30 of about 338,751 (320)
Antioxidants, 2022 Emerging evidence suggests that the intracellular clearance system plays a vital role in maintaining homeostasis and in regulating oxidative stress and inflammation in retinal pigment epithelium (RPE) cells. Dysfunctional proteasomes and autophagy in RPE
Iswariyaraja Sridevi Gurubaran +3 more
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The dynamics of a kinetic activator–inhibitor system
Journal of Differential Equations, 2006 The paper deals with the analysis of a reaction-diffusion system, proposed in [Kybernetik 12, No. 1, 30--39 (1972; Zbl 1434.92013)] by \textit{A. Gierer} and \textit{H. Meinhardt}, as a model for the regeneration phenomenon of hydra. The authors study in detail the steady states and the dynamics of the kinetic system, showing that it exhibits ...
Ni, Wei-Ming +2 more
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Cardiovascular risk associated with interactions among polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems. [PDF]
PLoS ONE, 2010 Vascular fibrinolytic balance is maintained primarily by interplay of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1).
John P Bentley +6 more
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The occurrence of prime numbers revisited
GECONTEC: Revista Internacional de Gestión del Conocimiento y la Tecnología, 2016 Based on an arithmetical and autocatalytic approach, the authors propose a solution for the occurrence of prime numbers. Exact arithmetical calculations are provided for: the closest prime to any given positive integer (or any number of bigger or smaller
Ernesto Tapia Moore, José Tapia Yañez
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Bifurcation and chaos in a discrete activator-inhibitor system
AIMS Mathematics, 2023 <abstract><p>In this paper, we explore local dynamic characteristics, bifurcations and control in the discrete activator-inhibitor system. More specifically, it is proved that discrete-time activator-inhibitor system has an interior equilibrium solution.
A. Q. Khan +5 more
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Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis [PDF]
, 2016 Funding The study was funded entirely by institutional funds.Peer ...
Galley, H. F. +4 more
core +1 more source
iScience, 2018 Summary: TUC338 is an ultraconserved long non-coding RNA that contributes to transformed cell growth in hepatocellular carcinoma (HCC). Genomic regions of TUC338 occupancy were enriched in unique or known binding motifs homologous to the tumor ...
Hui-Ju Wen +5 more
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Haematologica, 2022 Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling.
Katharina Woess +19 more
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A feedback quenched oscillator produces turing patterning with one diffuser. [PDF]
PLoS Computational Biology, 2012 Efforts to engineer synthetic gene networks that spontaneously produce patterning in multicellular ensembles have focused on Turing's original model and the "activator-inhibitor" models of Meinhardt and Gierer. Systems based on this model are notoriously
Justin Hsia +4 more
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Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase [PDF]
Angewandte Chemie International Edition, 2014 AbstractThe ceramides are a family of bioactive lipid‐derived messengers involved in the control of cellular senescence, inflammation, and apoptosis. Ceramide hydrolysis by acid ceramidase (AC) stops the biological activity of these substances and influences survival and function of normal and neoplastic cells.
Pizzirani, Daniela* +11 more
openaire +5 more sources