Results 31 to 40 of about 10,333,992 (256)
Robust network topologies for generating oscillations with temperature-independent periods.
PLoS ONE, 2017 Nearly all living systems feature a temperature-independent oscillation period in circadian clocks. This ubiquitous property occurs at the system level and is rooted in the network architecture of the clock machinery. To investigate the mechanism of this
Lili Wu, Qi Ouyang, Hongli Wang
doaj +1 more source
When cytokinin, a plant hormone, meets the adenosine A2A receptor: a novel neuroprotectant and lead for treating neurodegenerative disorders? [PDF]
PLoS ONE, 2012 It is well known that cytokinins are a class of phytohormones that promote cell division in plant roots and shoots. However, their targets, biological functions, and implications in mammalian systems have rarely been examined. In this study, we show that
Yi-Chao Lee +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Time of admission to PICU in relation to plasminogen-activator-inhibitor-1 levels and outcome.
, 2016 (A) Patients admitted between 6:00 am and 12:00 am had higher plasminogen-activator-inhibitor-1 levels than patients admitted at night (P = 0.019) or in the afternoon (P = 0.007). (PAI-1 level on y-axis in logarithmic scale.
Marjon H. Cnossen (3366872) +4 more
core +1 more source
Amplification without instability: applying fluid dynamical insights in chemistry and biology
New Journal of Physics, 2013 While amplification of small perturbations often arises from instability, transient amplification is possible locally even in asymptotically stable systems.
Jonathan H McCoy
doaj +1 more source
Ожирение и метаболизм, 2011 The aim of the study was to assess the effect of metformin plus lifestyle modification on procoagulant and proinflammatory state associated with metabolic syndrome in postmenopausal women. Materials and methods: The 12-month prospective, open, randomized
doaj +1 more source
MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model. [PDF]
PLoS ONE, 2018 The complement and coagulation systems closely interact with each other. These interactions are believed to contribute to the proinflammatory and prothrombotic environment involved in the development of thrombotic complications in many diseases ...
Lorenz Jenny +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh +4 more
wiley +1 more source
, 2015 Combination experiments of activators and inhibitors. (A) Mean log10 ADP release across platelets from 10 blood donors are shown, with green indicating platelet activation. Combinations of activator and inhibitors. Single and double doses (concentrations)
Denis C. Shields (18564) +5 more
core +1 more source
Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]
, 2001 Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Kellermann, Josef +10 more
core +1 more source