Results 21 to 30 of about 234,823 (303)

Bifurcation and chaos in a discrete activator-inhibitor system

open access: yesAIMS Mathematics, 2023
<abstract><p>In this paper, we explore local dynamic characteristics, bifurcations and control in the discrete activator-inhibitor system. More specifically, it is proved that discrete-time activator-inhibitor system has an interior equilibrium solution.
A. Q. Khan   +5 more
openaire   +2 more sources

Cardiovascular risk associated with interactions among polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems. [PDF]

open access: yesPLoS ONE, 2010
Vascular fibrinolytic balance is maintained primarily by interplay of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1).
John P Bentley   +6 more
doaj   +1 more source

Epoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells

open access: yesAntioxidants, 2022
Emerging evidence suggests that the intracellular clearance system plays a vital role in maintaining homeostasis and in regulating oxidative stress and inflammation in retinal pigment epithelium (RPE) cells. Dysfunctional proteasomes and autophagy in RPE
Iswariyaraja Sridevi Gurubaran   +3 more
doaj   +1 more source

The occurrence of prime numbers revisited

open access: yesGECONTEC: Revista Internacional de Gestión del Conocimiento y la Tecnología, 2016
Based on an arithmetical and autocatalytic approach, the authors propose a solution for the occurrence of prime numbers. Exact arithmetical calculations are provided for: the closest prime to any given positive integer (or any number of bigger or smaller
Ernesto Tapia Moore, José Tapia Yañez
doaj   +4 more sources

Functional Modulation of Gene Expression by Ultraconserved Long Non-coding RNA TUC338 during Growth of Human Hepatocellular Carcinoma

open access: yesiScience, 2018
Summary: TUC338 is an ultraconserved long non-coding RNA that contributes to transformed cell growth in hepatocellular carcinoma (HCC). Genomic regions of TUC338 occupancy were enriched in unique or known binding motifs homologous to the tumor ...
Hui-Ju Wen   +5 more
doaj   +1 more source

Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade

open access: yesHaematologica, 2022
Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling.
Katharina Woess   +19 more
doaj   +1 more source

A feedback quenched oscillator produces turing patterning with one diffuser. [PDF]

open access: yesPLoS Computational Biology, 2012
Efforts to engineer synthetic gene networks that spontaneously produce patterning in multicellular ensembles have focused on Turing's original model and the "activator-inhibitor" models of Meinhardt and Gierer. Systems based on this model are notoriously
Justin Hsia   +4 more
doaj   +1 more source

A stability index for travelling waves in activator-inhibitor systems

open access: yesProceedings of the Royal Society of Edinburgh: Section A Mathematics, 2019
AbstractWe consider the stability of nonlinear travelling waves in a class of activator-inhibitor systems. The eigenvalue equation arising from linearizing about the wave is seen to preserve the manifold of Lagrangian planes for a nonstandard symplectic form. This allows us to define a Maslov index for the wave corresponding to the spatial evolution of
Cornwell, Paul   +1 more
openaire   +3 more sources

Value of novel thrombotic markers for predicting occurrence of the malignant cerebral artery infarction: a prospective clinical study

open access: yesFrontiers in Neurology, 2023
ObjectiveThis study investigated the diagnostic performance of thrombin–antithrombin complex (TAT), plasmin–α2 plasmin inhibitor complex (PIC), tissue plasminogen activator–plasminogen activator inhibitor complex (t-PAIC), and thrombomodulin (TM) in ...
Xiaoxia Zhao   +6 more
doaj   +1 more source

Roles of calcium/calmodulin-dependent kinase II in long-term memory formation in crickets. [PDF]

open access: yesPLoS ONE, 2014
Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) is a key molecule in many systems of learning and memory in vertebrates, but roles of CaMKII in invertebrates have not been characterized in detail.
Makoto Mizunami   +4 more
doaj   +1 more source

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