Results 21 to 30 of about 10,333,992 (256)

Segregation and pursuit waves in activator-inhibitor systems [PDF]

, 2007
We investigate the effects of cross-diffusion on propagating waves in an activator-inhibitor system. The model consists of a piecewise linear approximation of FitzHugh-Nagumo kinetics and a cross-diffusion term for either the activator or the inhibitor ...
Horsthemke, Werner, Casas Vázquez, José, Zemskov, Evgeny P., Méndez, Vicenç   +3 more
core   +1 more source

A feedback quenched oscillator produces turing patterning with one diffuser. [PDF]

PLoS Computational Biology, 2012
Efforts to engineer synthetic gene networks that spontaneously produce patterning in multicellular ensembles have focused on Turing's original model and the "activator-inhibitor" models of Meinhardt and Gierer. Systems based on this model are notoriously
Justin Hsia, William J Holtz, Daniel C Huang, Murat Arcak, Michel M Maharbiz   +4 more
doaj   +1 more source

Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]

, 2003
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R., Wosikowski, K., Probst, C., Sander, C. A., Degitz, K., Schuh, T., Flaig, M. J., Braungart, E., Douwes, K., Magdolen, V., C.A. Sander, C. Probst, K. Wosikowski, K. Degitz, T. Schuh, R. Besch, E. Braungart, V. Magdolen, M.J. Flaig, K. Douwes   +19 more
core   +2 more sources

Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis [PDF]

, 2010
Background: Squamous cell carcinoma of the head and neck (SCCHN) are highly invasive tumours with frequent local and distant recurrence. Metastasis formation requires degradation of the extracellular matrix, which is fulfilled by membrane-associated ...
Olivier Gires, Muehlenweg Bernd, Pamela Zengel, Muehlenweg, Bernd, Gires, Olivier, Ramp, D., Gires, O., Alexander Berghaus, Gires Olivier, Mack, Brigitte, Zengel, Pamela, Zahler, Stefan, Muehlenweg, B., Diana Ramp, Stefan Zahler, Mack, B., Bernd Muehlenweg, Zahler, S., Berghaus Alexander, Mack Brigitte, Zengel, P., Suna Schmitz, Berghaus, Alexander, Schmitz, Suna, Schmitz, S., Ramp, Diana, Schmitz Suna, Zahler Stefan, Zengel Pamela, Brigitte Mack, Ramp Diana, Berghaus, A.   +31 more
core   +2 more sources

Urokinase-Type Plasminogen Activator Promotes Paracellular Transmigration of Neutrophils Via Mac-1, But Independently of Urokinase-Type Plasminogen Activator Receptor [PDF]

, 2011
Background: Urokinase-type plasminogen activator (uPA) has recently been implicated in the pathogenesis of ischemia-reperfusion (I/R) injury. The underlying mechanisms remain largely unclear.
Paul J. Declerck, Rehberg, Markus, Daniel Puhr-Westerheide, Lerchenberger, Max, Uhl, Bernd, Kanse, Sandip, Johanna Liebl, Reichel, Christoph A., Bernd Uhl, Markus Rehberg, Zahler, Stefan, Lorenzl, Stefan, Elisabeth Deindl, Khandoga, Andrej, Declerck, Paul J., Stefan Zahler, Schmalix, Wolfgang, Fritz Krombach, Liebl, Johanna, Christoph A. Reichel, Krombach, Fritz, Max Lerchenberger, Andrej Khandoga, Stefan Lorenzl, Deindl, Elisabeth, Wolfgang Schmalix, Puhr-Westerheide, Daniel, Sandip Kanse   +27 more
core   +1 more source

Vitamin D Deficiency is Associated With Increased Plasminogen Activator Inhibitor 1/Plasminogen Activator Inhibitor 2 Ratio in Pregnancy [PDF]

, 2023
Background Vitamin D deficiency has recently been suggested as an independent risk factor for thrombosis. Notably, vitamin D deficiency is common in pregnant populations, whom already have an increased thrombotic risk.
Pinar Bor MD, PhD, Anna Louise Vestergaard MD, PhD, Mustafa Vakur Bor MD, PhD, Yaseelan Palarasah MS, PhD, Agnete Larsen MD, PhD, Isabella Hangaard Rüdiger MD, Matilde Kanstrup Andersen BA   +6 more
core   +2 more sources

Value of novel thrombotic markers for predicting occurrence of the malignant cerebral artery infarction: a prospective clinical study

Frontiers in Neurology, 2023
ObjectiveThis study investigated the diagnostic performance of thrombin–antithrombin complex (TAT), plasmin–α2 plasmin inhibitor complex (PIC), tissue plasminogen activator–plasminogen activator inhibitor complex (t-PAIC), and thrombomodulin (TM) in ...
Xiaoxia Zhao, Siyu Yang, Ruining Lei, Yi Liu, Qiaoyan Duan, Jundong Li, Lei Sun   +6 more
doaj   +1 more source

The effects of residual platelets in plasma on plasminogen activator inhibitor-1 and plasminogen activator inhibitor-1-related assays. [PDF]

, 2017
Due to controversial evidence in the literature pertaining to the activity of plasminogen activator inhibitor-1 in platelets, we examined the effects of residual platelets present in plasma (a potential pre-analytical variable) on various plasminogen ...
Sunelle A Barnard, Barnard, SA, Du Toit Loots, Dingeman C Rijken, Du Toit Loots (3716449), Loots, DT, Marlien Pieters, Sunelle A. Barnard (3716446), Rijken, Dingeman C., Marlien Pieters (299650), Pieters, M. (Marlien), Loots, D.T. (Du Toit), Pieters, Marlien, Rijken, D.C. (Dingeman), Rijken, Dick, Pieters, M, Loots, Du Toit, Barnard, S.A. (Sunelle A.), Dingeman C. Rijken (299652), Barnard, Sunelle A., Barnard Sunelle A., Pieters Marlien, Loots Du Toit, Rijken Dingeman C.   +23 more
core   +1 more source

Roles of calcium/calmodulin-dependent kinase II in long-term memory formation in crickets. [PDF]

PLoS ONE, 2014
Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) is a key molecule in many systems of learning and memory in vertebrates, but roles of CaMKII in invertebrates have not been characterized in detail.
Makoto Mizunami, Yuko Nemoto, Kanta Terao, Yoshitaka Hamanaka, Yukihisa Matsumoto   +4 more
doaj   +1 more source

Clinical study on the feasibility of new thrombus markers in predicting massive cerebral infarction

Frontiers in Neurology, 2023
ObjectiveThis study investigated the diagnostic performance of the thrombin-antithrombin complex (TAT), plasmin-α2 plasmin inhibitor complex (PIC), tissue plasminogen activator-plasminogen activator inhibitor complex (t-PAIC), and thrombomodulin (TM) in ...
Xiaoxia Zhao, Siyu Yang, Ruining Lei, Qiaoyan Duan, Jundong Li, Jiangtao Meng, Lei Sun   +6 more
doaj   +1 more source