Results 51 to 60 of about 234,823 (303)
Diffusivity estimation for activator–inhibitor models: Theory and application to intracellular dynamics of the actin cytoskeleton [PDF]
, 2021 A theory for diffusivity estimation for spatially extended activator–inhibitor dynamics modeling the evolution of intracellular signaling networks is developed in the mathematical framework of stochastic reaction–diffusion systems.
Beta, Carsten +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Instability mechanisms of repelling peak solutions in a multi-variable activator–inhibitor system
Chaos: An Interdisciplinary Journal of Nonlinear Science, 2022 We study the linear stability properties of spatially localized single- and multi-peak states generated in a subcritical Turing bifurcation in the Meinhardt model of branching. In one spatial dimension, these states are organized in a foliated snaking structure owing to peak–peak repulsion but are shown to be all linearly unstable, with the number of ...
Edgar Knobloch, Arik Yochelis
openaire +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Journal of Emergencies, Trauma and Shock, 2013 Background: Tissue injury increases blood levels of extracellular histones and nucleic acids, and these may influence hemostasis, promote inflammation and damage the endothelium. Trauma-induced coagulopathy (TIC) may result from an endogenous response to
Pär I Johansson +4 more
doaj +1 more source
A priori estimates of stationary solutions of an activator-inhibitor system [PDF]
Indiana University Mathematics Journal, 2007 We consider positive solutions of the stationary Gierer-Meinhardt system. Under suitable conditions on the exponents $p,q,r$ and $s$, different types of a priori estimates are obtained, existence and non-existence results of nontrivial solutions are derived, for both positive and zero source production cases.
Jiang, Huiqiang, Ni, Wei-Ming
openaire +2 more sources
Turing instabilities in general systems
, 2000 We present necessary and sufficient conditions on the stability matrix of a general n(S2)-dimensional reaction-diffusion system which guarantee that its uniform steady state can undergo a Turing bifurcation.
Satnoianu, RA +5 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Activator-Inhibitor Control of Tissue Growth
, 1991 This note develops a simple model for the competition between activator and inhibitor control mechanisms in one-dimensional tissue growth. The pedagogic usefulness of such a model is that it is easily accessible to undergraduate applied mathematicians ...
Adam, John A.
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source