Results 71 to 80 of about 214,445 (261)
Global existence of solutions of an activator-inhibitor system
Discrete and Continuous Dynamical Systems, 2006 We consider the generalized Gierer-Meinhardt system $\frac{\partial u_{j}}{\partial t}=d_{j}$Δ $u_{j}- a_{j}u_{j} +g_{j}(x,u) \ \ \text{in}\ \ \Omega\times[0,T) $ , $\frac{\partial u_{j}}{\partial\nu}=0\ \ \text{on}\ \ \partial\Omega\times[ 0,T) $, $u_{j}(x,0) =\varphi_{j}(x)\ \ \text{in}\ \ \Omega$ where $\Omega$ is a smooth ...
openaire +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Mathematical modeling of traveling autosolitons in fractional-order activator-inhibitor systems [PDF]
Bulletin of the Polish Academy of Sciences: Technical Sciences, 2018 B. Datsko, V. Gafiychuk
doaj +1 more source
PLoS ONE, 2014 In recent years members of the tripartite motif-containing (TRIM) family of E3 ubiquitin ligases have been shown to both positively and negatively regulate viral defence and as such are emerging as compelling targets for modulating the anti-viral immune ...
Claire Wynne +10 more
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Frontiers in ImmunologyThe hemostatic system prevents and stops bleeding, maintaining circulatory integrity after injury. It directly interacts with the complement system, which is key to innate immunity.
Didar Murad +2 more
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Neoplasia: An International Journal for Oncology Research, 2005 Angiogenesis and tumor expansion are associated with extracellular matrix remodeling and involve various proteases such as the plasminogen (Pig)/plasminogen activator (PA) system.
Catherine Maillard +13 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Dilution and titration of cell-cycle regulators may control cell size in budding yeast.
PLoS Computational Biology, 2018 The size of a cell sets the scale for all biochemical processes within it, thereby affecting cellular fitness and survival. Hence, cell size needs to be kept within certain limits and relatively constant over multiple generations.
Frank S Heldt +3 more
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