Results 91 to 100 of about 10,333,992 (256)
Dilution and titration of cell-cycle regulators may control cell size in budding yeast.
PLoS Computational Biology, 2018 The size of a cell sets the scale for all biochemical processes within it, thereby affecting cellular fitness and survival. Hence, cell size needs to be kept within certain limits and relatively constant over multiple generations.
Frank S Heldt +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Frontiers in EndocrinologyBackground and aimsA prothrombotic state was demonstrated in patients with Cushing’s syndrome and is involved in the development and progression of cardiovascular and renal damage in hypertensive patients.
Gabriele Brosolo +9 more
doaj +1 more source
Journal of Pharmacological Sciences, 2007 The cardiovascular diseases are closely related to circadian rhythm, which is under the control of the biological clock. Clock genes show circadian oscillation not only in the suprachiasmatic nucleus but also in peripheral tissues, suggesting the ...
Koji Maemura +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Plant roots: Activator-Inhibitor model with dimerization.
, 2013 A, steady state values of inhibitor (solid), activator (dashed) and gene activity (dash-dotted) in dependence of internal zinc concentration. B, steady state gene activity in dependence of internal zinc status for varying .
Andrés Chavarría-Krauser (319991) +1 more
core +1 more source
Modern ideas of the role of the immune process and hemostasis in the pathogenesis of sepsis
Acta Biomedica ScientificaThe pathogenesis of sepsis as a pathological process, which is based on the body’s reaction in the form of generalized (systemic) inflammation to an infection of various nature, leading to acute multi-organ dysfunction, includes changes in the immune ...
M. V. Osikov +4 more
doaj +1 more source
Control of transversal instabilities in reaction-diffusion systems
New Journal of Physics, 2018 In two-dimensional reaction-diffusion systems, local curvature perturbations on traveling waves are typically damped out and vanish. However, if the inhibitor diffuses much faster than the activator, transversal instabilities can arise, leading from flat
Sonja Totz +3 more
doaj +1 more source
The effect of light quality on the expression of stomatal development genes of maize
Photosynthetica, 2019 Light-induced stomatal development is mediated through a crosstalk between cryptochrome (CRY), phytochrome (phy), and constitutive photomorphogenic 1 (COP1)-signaling systems.
T.D. LIU, X.W. ZHANG, Y. XU
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source