Results 11 to 20 of about 262,173 (350)

Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance [PDF]

open access: yes, 2013
Alfredo Ghezzi, Harish R. Krishnan, Linda Lew, Francisco J. Prado III, Darryl S. Ong, Nigel S. Atkinson, Section of Neurobiology and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas, United States of ...
Atkinson, Nigel S.   +5 more
core   +7 more sources

Genetic activity during early plant embryogenesis [PDF]

open access: yesBiochemical Journal, 2020
Seeds are essential for human civilization, so understanding the molecular events underpinning seed development and the zygotic embryo it contains is important. In addition, the approach of somatic embryogenesis is a critical propagation and regeneration strategy to increase desirable genotypes, to develop new genetically modified plants to meet ...
Ran Tian   +3 more
openaire   +2 more sources

About Epizootic Situation on Major Helminthosis of Different Breeds of Pigs in Georgia

open access: yesРоссийский паразитологический журнал, 2020
The purpose of the research is to study the epizootic situation on major helminthosis of different breed groups of pigs in Georgia. Materials and methods.
L. M. Udzhmadzhuridze   +3 more
doaj   +1 more source

Genetic control of active neural circuits [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2009
The use of molecular tools to study the neurobiology of complex behaviors has been hampered by an inability to target the desired changes to relevant groups of neurons. Specific memories and specific sensory representations are sparsely encoded by a small fraction of neurons embedded in a sea of morphologically and functionally similar cells.
Leon Reijmers   +3 more
openaire   +3 more sources

Target identification strategies in plant chemical biology [PDF]

open access: yes, 2014
The current needs to understand gene function in plant biology increasingly require more dynamic and conditional approaches opposed to classic genetic strategies.
Dejonghe, Wim, Russinova, Eugenia
core   +8 more sources

Genome-Wide Multiple Sclerosis Association Data and Coagulation [PDF]

open access: yes, 2019
The emerging concept of a crosstalk between hemostasis, inflammation, and immune system prompt recent works on coagulation cascade in multiple sclerosis (MS).
Arianna Fornasiero   +10 more
core   +2 more sources

Functional Modulation of Gene Expression by Ultraconserved Long Non-coding RNA TUC338 during Growth of Human Hepatocellular Carcinoma

open access: yesiScience, 2018
Summary: TUC338 is an ultraconserved long non-coding RNA that contributes to transformed cell growth in hepatocellular carcinoma (HCC). Genomic regions of TUC338 occupancy were enriched in unique or known binding motifs homologous to the tumor ...
Hui-Ju Wen   +5 more
doaj   +1 more source

Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analysesResearch in context

open access: yesEBioMedicine, 2023
Summary: Background: Identifying new drug targets for inflammatory bowel disease (IBD) is urgently needed. The proteome is a major source of therapeutic targets.
Jie Chen   +11 more
doaj   +1 more source

Identification and characterization of a Mef2 transcriptional activator in schistosome parasites. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
Myocyte enhancer factor 2 protein (Mef2) is an evolutionarily conserved activator of transcription that is critical to induce and control complex processes in myogenesis and neurogenesis in vertebrates and insects, and osteogenesis in vertebrates.
John N Milligan, Emmitt R Jolly
doaj   +1 more source

Genetic Dissection of Antibiotic Adjuvant Activity

open access: yesmBio, 2022
One strategy to confront the antibiotic resistance crisis is through the development of adjuvant compounds that increase the efficacy of established drugs. A key step in the development of a natural product adjuvant as a drug is identifying the resistance process it undermines to enhance antibiotic activity.
J. Bailey   +6 more
openaire   +3 more sources

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