Results 11 to 20 of about 3,963,692 (395)

Genetics of plasma paroxonase activity [PDF]

open access: yesJournal of Medical Genetics, 1982
Complex segregation analysis of plasma paroxonase activity gives evidence for a major locus with incomplete dominance (d = 0·70) causing high activity plus a background of multifactorial inheritance (heritability = 0·09).
L, Iselius, D A, Evans, J R, Playfer
openaire   +2 more sources

PRMT5 Cooperates with pICln to Function as a Master Epigenetic Activator of DNA Double-Strand Break Repair Genes

open access: yesiScience, 2020
Summary: DNA double-strand break (DSB) repair is critical for cell survival and genome integrity. Upon recognition of DSBs, repair proteins are transiently upregulated to facilitate repair through homologous recombination (HR) or non-homologous end ...
Jake L. Owens   +9 more
doaj   +1 more source

The Genetic Activity Profile Database [PDF]

open access: yesEnvironmental Health Perspectives, 1991
A graphic approach termed a Genetic Activity Profile (GAP) has been developed to display a matrix of data on the genetic and related effects of selected chemical agents. The profiles provide a visual overview of the quantitative (doses) and qualitative (test results) data for each chemical.
M D, Waters   +3 more
openaire   +3 more sources

Genetic activity during early plant embryogenesis [PDF]

open access: yesBiochemical Journal, 2020
Seeds are essential for human civilization, so understanding the molecular events underpinning seed development and the zygotic embryo it contains is important. In addition, the approach of somatic embryogenesis is a critical propagation and regeneration strategy to increase desirable genotypes, to develop new genetically modified plants to meet ...
Ran Tian   +3 more
openaire   +2 more sources

Genetic control of active neural circuits [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2009
The use of molecular tools to study the neurobiology of complex behaviors has been hampered by an inability to target the desired changes to relevant groups of neurons. Specific memories and specific sensory representations are sparsely encoded by a small fraction of neurons embedded in a sea of morphologically and functionally similar cells.
Leon Reijmers   +3 more
openaire   +3 more sources

About Epizootic Situation on Major Helminthosis of Different Breeds of Pigs in Georgia

open access: yesРоссийский паразитологический журнал, 2020
The purpose of the research is to study the epizootic situation on major helminthosis of different breed groups of pigs in Georgia. Materials and methods.
L. M. Udzhmadzhuridze   +3 more
doaj   +1 more source

Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

open access: yesSignal Transduction and Targeted Therapy, 2020
Based on engineered or bacterial nucleases, the development of genome editing technologies has opened up the possibility of directly targeting and modifying genomic sequences in almost all eukaryotic cells.
Hongyi Li   +5 more
semanticscholar   +1 more source

Target identification strategies in plant chemical biology [PDF]

open access: yes, 2014
The current needs to understand gene function in plant biology increasingly require more dynamic and conditional approaches opposed to classic genetic strategies.
Dejonghe, Wim, Russinova, Eugenia
core   +8 more sources

Functional Modulation of Gene Expression by Ultraconserved Long Non-coding RNA TUC338 during Growth of Human Hepatocellular Carcinoma

open access: yesiScience, 2018
Summary: TUC338 is an ultraconserved long non-coding RNA that contributes to transformed cell growth in hepatocellular carcinoma (HCC). Genomic regions of TUC338 occupancy were enriched in unique or known binding motifs homologous to the tumor ...
Hui-Ju Wen   +5 more
doaj   +1 more source

Genome-Wide Multiple Sclerosis Association Data and Coagulation [PDF]

open access: yes, 2019
The emerging concept of a crosstalk between hemostasis, inflammation, and immune system prompt recent works on coagulation cascade in multiple sclerosis (MS).
Arianna Fornasiero   +10 more
core   +2 more sources

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