Results 21 to 30 of about 41,601 (250)

Method of the Metronidazole and Clotrimazole administration in the content of the emulsion basis

Zaporožskij Medicinskij Žurnal, 2013
Proved optimum method of administration of active pharmaceutical ingredients – metronidazole and clotrimazole – in the emulsion base of ointment as a suspension with vaseline oil.
V. V. Rudenko, S. V. Biryukova
doaj   +1 more source

Light-sensitive medicinal compounds – the actual review of studies and strategies in proceedings [PDF]

Farmacja Polska, 2019
The main procedure for stability testing of Active Pharmaceutical Ingredients (API) and medicinal products is described in the guidelines of the International Council for the Harmonization of Technical Requirements for Human Drugs (ICH).
Marzena Jamrógiewicz, Aneta Karczewska-Kaliszak, Karolina Milewska   +2 more
doaj   +1 more source

Crystal Structure and Solid-State Conformational Analysis of Active Pharmaceutical Ingredient Venetoclax

Crystals, 2021
Venetoclax is an orally bioavailable, B-cell lymphoma-2 selective inhibitor used for the treatment of chronic lymphocytic leukemia, small lymphocytic lymphoma, and acute myeloid leukemia.
Franc Perdih, Nina Žigart, Zdenko Časar   +2 more
doaj   +1 more source

Development and validation of alternative methods by non-aqueous acid-base titration and derivative ultraviolet spectrophotometry for quantification of sildenafil in raw material and tablets

Brazilian Journal of Pharmaceutical Sciences, 2017
Sildenafil citrate (SILC) is a potent phosphodiesterase-5 inhibitor used for erectile dysfunction and pulmonary hypertension. This study shows two simple, fast and alternative analytical methods for SILC determination by non-aqueous titration and by ...
Taízia Dutra Silva, Cibele Rodrigues Toledo, Cristina Duarte Vianna-Soares   +2 more
doaj   +1 more source

A Novel Formulation of Fosamprenavir Calcium: Therapeutic Deep Eutectic Solvent with Enhanced Properties

Crystals
In the pharmaceutical industry, deep eutectic solvents can be used to enhance the solubility, permeability, and absorption of active pharmaceutical ingredients.
Jasna Prlić Kardum, Iva Zokić, Aleksandra Sander, Patricija Pelin   +3 more
doaj   +1 more source

Agglomeration Control during Ultrasonic Crystallization of an Active Pharmaceutical Ingredient

Crystals, 2017
Application of ultrasound during crystallization can efficiently inhibit agglomeration. However, the mechanism is unclear and sonication is usually enabled throughout the entire process, which increases the energy demand. Additionally, improper operation
Bjorn Gielen, Jeroen Jordens, Leen C. J. Thomassen, Leen Braeken, Tom Van Gerven   +4 more
doaj   +1 more source

Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications

Acta Pharmaceutica Sinica B, 2021
Pharmaceutical cocrystals are multicomponent systems in which at least one component is an active pharmaceutical ingredient and the others are pharmaceutically acceptable ingredients.
Minshan Guo, Xiaojie Sun, Jiahui Chen, Ting Cai   +3 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Interpretation of Guidelines for Occupational Hazard Assessment and Control of Active Pharmaceutical Ingredient in the Pharmaceutical Industry (T/WSJD60—2024)

环境与职业医学
The Guidelines for Occupational Hazard Assessment and Control of Active Pharmaceutical Ingredient in the Pharmaceutical Industry (T/WSJD 60—2024) is the first guiding standard in the field of health in China that focuses on occupational health protection
Ying TANG, Jian CHEN, Tao LI, Huifang YAN, Yongqing CHEN, Yi XU, Yong NING, Man YU, Chenyi TAO, Xia ZHANG   +9 more
doaj   +1 more source

Exploring the Effects of Cramped-Impact-Type Mechanical Action on Active Pharmaceutical Ingredient (Levofloxacin)—Prospects for Pharmaceutical Applications

Powders, 2023
Mechanochemistry is one of the ten great discoveries of green chemistry methods for synthesizing new substances. A drug substance from the fluoroquinolone group was exposed to high-intensity mechanical impacts using a laboratory knife mill for 21 min and
Elena Uspenskaya, Anastasia Simutina, Ekaterina Kuzmina, Vasilisa Sukhanova, Timur Garaev, Tatiana Pleteneva, Alena Koldina, Ekaterina Kolyabina, Gleb Petrov, Anton Syroeshkin   +9 more
doaj   +1 more source