Results 151 to 160 of about 8,578,817 (287)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Everard Range - Mount Illbillie in background [picture] /

, 1891
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an6647833 ...
Elliott, Frederick, active 1855-1897.
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Birksgate Range - looking north [picture] /

, 1891
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an6647833 ...
Elliott, Frederick, active 1855-1897.
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Functional Dissection of a Wheat NLR Protein Reveals a Minimal Active Region and Key Regulatory Sites for Immune Signalling. [PDF]

Mol Plant Pathol
Zhu X, Jiang S, Zhao J, Peng F, Zhao R, Li X, Luo Y, Xiong Z, Li Q, Rolland F, Kang Z, Wang X, Liu Y, Huang L, Wang X.   +14 more
europepmc   +1 more source

Govets Leap Waterfall [N.S.W., 1878] [picture] /

, 1878
Title taken from below the photograph.; "38"--Inscription lower left corner.; "A clear fall of 580 feet - Blue Mountains"--Below title.; Part of collection: Photographic illustrations of New South Wales 1878.; Also available in an electronic version via ...
Brodie, Alexander, active 1867-1891.
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Combined Surface Flux Transport and Helioseismic Far-Side Active Region Model (FARM). [PDF]

Sol Phys
Yang D, Heinemann SG, Cameron RH, Gizon L.   +3 more
europepmc   +1 more source

Grand view of Govets Leap Gorge [N.S.W., 1878] [picture] /

, 1878
Title taken from below the photograph.; "40"--Inscription lower left corner.; Part of collection: Photographic illustrations of New South Wales 1878.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Brodie, Alexander, active 1867-1891.
core