Results 141 to 150 of about 12,305 (210)

Activin levels correlate with lymphocytic infiltration in epithelial ovarian cancer

open access: yesCancer Medicine
Objective The TGF‐β superfamily member activin, a dimer of the gene products of INHBA and/or INHBB, has been implicated in immune cell maturation and recruitment, but its immune impact within epithelial ovarian cancer (EOC) is not well characterized.
Elizabeth T. Evans   +6 more
doaj   +1 more source

Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]

open access: yes, 2010
Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Vinay Varadan   +3 more
core  

Reframing Natural Killer Cell Biology for Cancer: From Cytotoxic Potential to Context‐Matched Immune States

open access: yesMedComm – Oncology, Volume 5, Issue 4, December 2026.
Natural killer (NK) cells in cancer occupy context‐dependent states shaped by exposure history, tissue adaptation, and tumor ecology. Therapeutic success requires matching NK‐cell products to dominant ecological constraints rather than relying on cytotoxicity alone.
Jinyi Dong   +4 more
wiley   +1 more source

Benchmarking commercial large language models for gene–disease–phenotype extraction from full‐text human genetics literature

open access: yesQuantitative Biology, Volume 14, Issue 4, December 2026.
Abstract Manual curation of gene–disease–phenotype relationships from the human genetics literature is a persistent bottleneck for maintaining its bioinformatics databases. Whereas large language models (LLMs) offer a promising alternative, there is currently no systematic benchmark that evaluates whether state‐of‐the‐art commercial LLMs can perform ...
Danqing Yin   +6 more
wiley   +1 more source

Associations Between Weight Loss Prior to Knee and Hip Arthroplasty and Peri‐ and Post‐Operative Outcomes: A Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, Volume 27, Issue 12, December 2026.
ABSTRACT Background In some of the existing literature, obesity is associated with increased complications in those who undergo lower limb arthroplasty. We conducted a systematic review and meta‐analysis to assess if pre‐arthroplasty weight loss mitigates increased post‐operative risks. Methods This systematic review and meta‐analysis was registered on
Moneet Gill   +5 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, Volume 600, Issue 21, Page 3186-3200, November 2026.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Hereditary Hemorrhagic Telangiectasia of the Tongue: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant vascular disorder that may involve the oral mucosa, providing important diagnostic clues for dental practitioners. This report describes a 54‐year‐old female presenting with recurrent bleeding from multiple red‐purple telangiectatic papules on the dorsal surface of the ...
Saede Atarbashi‐Moghadam   +5 more
wiley   +1 more source

Müller Glia Subtypes Define Neuro‐Glial Associations and Spatial Morphogen Axes in the Zebrafish Retina

open access: yesGlia, Volume 74, Issue 11, November 2026.
Zebrafish Müller glia are heterogeneous in the early larval retina. Zebrafish Müller glia subtypes define a spatial axis of retinoic acid metabolism. Neuron‐associated glial programs identified in Zebrafish Müller glia are evolutionarily conserved in mammals. ABSTRACT Müller glia are instrumental macroglia of the vertebrate retina, once thought to be a
Samuel S. Storey   +3 more
wiley   +1 more source

Activin A [PDF]

open access: yesScience-Business eXchange, 2010
openaire   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for ependymomas

open access: yesBrain Pathology, Volume 36, Issue 6, November 2026.
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Laveniya Satgunaseelan   +13 more
wiley   +1 more source

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