Results 11 to 20 of about 158,807,029 (257)

Activin-A up-regulates type I activin receptor mRNA levels in human immortalized extravillous trophoblast cells. [PDF]

Reproductive Biology and Endocrinology, 2003
Activin is known to play an important regulatory role in reproduction, including pregnancy. To further examine the role and signaling mechanism of activin in regulating placental function, the steady-state level of activin type I receptor (ActRI) mRNA in
Leung Peter CK, Peng Chun, Chen Victor TS   +2 more
doaj   +2 more sources

Activin A In Brain Injury

, 2007
Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins ...
Florio, Pasquale, Gazzolo, Diego, Luisi, Stefano, Petraglia, Felice   +3 more
openaire   +4 more sources

Activin A in Mammalian Physiology. [PDF]

Physiological Reviews, 2019
Activins are dimeric glycoproteins belonging to the transforming growth factor beta superfamily and resulting from the assembly of two beta subunits, which may also be combined with alpha subunits to form inhibins.
E. Bloise, P. Ciarmela, C. Dela Cruz, S. Luisi, F. Petraglia, F. Reis   +5 more
semanticscholar   +5 more sources

Activin A regulates activation of mouse neutrophils by Smad3 signalling [PDF]

Open Biology, 2017
Activin A, a member of the transforming growth factor beta superfamily, acts as a pro-inflammatory factor in acute phase response, and influences the pathological progress of neutrophil-mediated disease.
Yan Qi, Jingyan Ge, Chunhui Ma, Na Wu, Xueling Cui, Zhonghui Liu   +5 more
doaj   +1 more source

Enhanced Expression of Recombinant Activin A in Escherichia coli by Optimization of Induction Parameters [PDF]

Journal of Sciences, Islamic Republic of Iran, 2018
Activin A is a member of the transforming growth factor β super family. Because of its extensive clinical usages, its recombinant production is beneficial. In this study, activin A was expressed in E. coli using the pET 21a expression vector.
Z. Hajihassan, N. Biroonro
doaj   +1 more source

Activins and activin antagonists in hepatocellular carcinoma [PDF]

World Journal of Gastroenterology, 2008
In many parts of the world hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality but the underlying molecular pathology is still insufficiently understood. There is increasing evidence that activins, which are members of the transforming growth factor beta (TGFbeta) superfamily of growth and differentiation factors ...
Alev, Deli, Emanuel, Kreidl, Stefan, Santifaller, Barbara, Trotter, Katja, Seir, Walter, Berger, Rolf, Schulte-Hermann, Chantal, Rodgarkia-Dara, Michael, Grusch   +8 more
openaire   +2 more sources

Serum levels of Activin A: Marker of insulin resistance and cardiovascular risk in prediabetics

Journal of Family Medicine and Primary Care, 2022
Background: A substantial proportion of health burden in diabetic individuals can be attributed to cardiovascular complications. The increasing risk of cardiovascular complications along the spectrum of dysglycemia warrants the need to devise novel ...
Ajay Chauhan, Asmita Gupta, Parul Goyal, Tarun Kumar   +3 more
doaj   +1 more source

Laboratory Markers in the Prediction of Premature Birth

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2023
The problem of premature birth (PB) remains topical for the practicing obstetrician-gynecologist. The study of marker proteins indicating an increased risk of PB is one of the relevant areas of interest in modern obstetrics.
Evgenia Igorevna Popova, Andrey Vladimirovich Kozlov, Arina Ilinichna Sizova, Artem Viktorovich Lyamin, Oksana Anatolyevna Gusyakova, Alena Anatolyevna Ereshchenko   +5 more
doaj   +1 more source

A Novel Signal Peptide Derived from Bacillus Licheniformis α-Amylase Efficiently Targets Recombinant Human Activin A to the Periplasm of Escherichia coli [PDF]

Journal of Cell and Molecular Research, 2018
Human activin A is a member of the transforming growth factor-β superfamily consists of two similar beta subunits. Activin A is expressed by different cells and displays numerous biological activities such as control of neuronal cell proliferation and ...
Zahra Hajihassan, Seyed kazem Hosseini, Alireza Zomorodipour   +2 more
doaj   +1 more source

Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Among the major health challenges for astronauts during prolonged space travel are loss of muscle mass and loss of bone mass. Here, we investigated the effects of targeting the signaling pathway mediated by the secreted signaling molecules ...
Se-Jin Lee, A. Lehar, J. Meir, C. Koch, Andrew Morgan, L. Warren, Renata Rydzik, D. Youngstrom, Harshpreet Chandok, J. George, J. Gogain, M. Michaud, T. Stoklasek, Y. Liu, Emily L. Germain-Lee   +14 more
semanticscholar   +1 more source