Results 211 to 220 of about 59,022 (255)
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Activin A in Perinatal Brain Injury
Neuropediatrics, 2015Activin A is a multifunctional growth and differentiation factor belonging to the transforming growth factor β (TGF-β) family. Growing evidence indicates its role as a neurotrophic factor and regulator of synaptic transmission as well as its functional importance in several types of cerebral injury.
Florian A, Brackmann +2 more
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Activin A Induces Apoptotic Cell Death
Biochemical and Biophysical Research Communications, 1993Activins, members of a family of the transforming growth factor beta (TGF beta), are involved in the regulation of multiple biological events. We found a novel effect of activin A on hybridoma and myeloma cell lines. Activin A exhibited a cytotoxic effect on interleukin-6 (IL-6)-dependent B9 cells and induced a significant increase in the proportion of
T, Nishihara, N, Okahashi, N, Ueda
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Journal of Cellular Physiology, 2010
AbstractActivin A, is a multifunctional cytokine of the transforming growth factor‐β superfamily of growth factors. This molecule has been shown to be implicated in the regulation of a broad range of important biological functions including bone remodelling.
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AbstractActivin A, is a multifunctional cytokine of the transforming growth factor‐β superfamily of growth factors. This molecule has been shown to be implicated in the regulation of a broad range of important biological functions including bone remodelling.
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Activin as a cell differentiation factor
Progress in Growth Factor Research, 1990Activin, originally discovered as a polypeptide hormone that is capable of stimulating follicle-stimulating hormone secretion from pituitary cells in vitro, has recently been found to have a much wider range of biological activities. There are a number of reports of activin action as a cell differentiation factor on various types of cells rather than ...
N, Ueno, S, Nishimatsu, K, Murakami
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Biochemical and Biophysical Research Communications, 1994
Activin A-, AB- and B-responding cells were characterized by their responsiveness in cytosolic free calcium ([Ca2+])i) to four hypothalamic releasing hormones, CRH, GHRH, TRH and GnRH. First, rat pituitary cells responding to activin A, AB and B in [Ca2+]i were determined in a mixed population of pituitary cells. The populations of the activin A-, AB-,
K, Tasaka +7 more
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Activin A-, AB- and B-responding cells were characterized by their responsiveness in cytosolic free calcium ([Ca2+])i) to four hypothalamic releasing hormones, CRH, GHRH, TRH and GnRH. First, rat pituitary cells responding to activin A, AB and B in [Ca2+]i were determined in a mixed population of pituitary cells. The populations of the activin A-, AB-,
K, Tasaka +7 more
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Blood, 2011
In this issue of Blood , Sierra-Filardi and colleagues shed new light on the still poorly understood proinflammatory role of Activin A in macrophage polarization ...
Sozzani S, MUSSO, Tiziana
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In this issue of Blood , Sierra-Filardi and colleagues shed new light on the still poorly understood proinflammatory role of Activin A in macrophage polarization ...
Sozzani S, MUSSO, Tiziana
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Quantitative two-site enzyme-linked immunosorbent assays for inhibin A, activin A and activin B
Human Reproduction, 1993We have developed three specific enzyme-linked immunosorbent assay (ELISA) formats which quantitate inhibin A in conditioned media and serum. The assays are sensitive in a range 0.078-5.0 ng/ml and have been characterized in terms of cross-reactivity to inhibin related proteins. The CK:CK assay format recognizes inhibin A, inhibin B and inhibin-related
T, Woodruff +8 more
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ACTIVIN AND ACTIVIN RECEPTORS IN A RAT OSTEOGENIC-SARCOMA CELL-LINE, UMR-106
International Journal of Oncology, 1995We have localized immunocytochemically activin-A-like reactivity in UMR-106 osteogenic cells with a characterized, specific antiserum against synthetic fragment of subunits of activin-A, a member of transforming growth factor B (TGFB) superfamily.
S, Ying, Z, Zhang, G, Huang, Y, Batres
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Activin A and hepatocyte growth regulation
Hepatology, 1994The present study was conducted to examine the effect of activin A on growth of rat hepatocytes. EGF induced a 10-fold increase in DNA synthesis as assessed by [3H]thymidine incorporation in cultured hepatocytes. When activin A was added together with EGF, DNA synthesis induced by EGF was markedly inhibited.
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Activin is a nerve cell survival molecule
Nature, 1990The structures of five neurotrophic molecules have so far been published. Nerve growth factor, fibroblast growth factor and purpurin, have been identified as nerve-cell survival molecules. More recently, brain-derived neurotrophic factor (BDNF) and ciliary neurotrophic factor have been cloned and sequenced.
D, Schubert +5 more
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