AnimalsActivin is a dimeric growth factor with diverse biological activities in vertebrates. This study aimed to investigate the regulatory role of the activin signaling pathway in the ovary of the endangered, cultured sturgeon species Acipenser sinensis.
Huamei Yue +4 more
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Physiological roles of activins in the human ovary
Journal of Bio-X Research, 2018 . Initially discovered in the pituitary as stimulators of follicle stimulating hormone, activins are homo- or heterodimers of inhibin subunits, which belong to the transforming growth factor-β superfamily.
Hsun-Ming Chang, Peter C.K. Leung
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Phylogenomic analyses reveal the evolutionary origin of the inhibin alpha-subunit, a unique TGFbeta superfamily antagonist. [PDF]
PLoS ONE, 2010 Transforming growth factor-beta (TGFbeta) homologues form a diverse superfamily that arose early in animal evolution and control cellular function through membrane-spanning, conserved serine-threonine kinases (RII and RI receptors).
Jie Zhu +10 more
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βA- and βC-activin, follistatin, activin receptor mRNA and βC-activin peptide expression during rat liver regeneration [PDF]
Journal of Molecular Endocrinology, 2005 The mRNA expression of two activin growth factor subunits (βA- and βC-activin), activin receptor subunits (ActRIIA, ActRIIB) and the activin-binding protein follistatin, and peptide expression of βA-activin and βC-activin subunits, were examined in regenerating rat liver after partial hepatectomy (PHx).
Gold, E +7 more
openaire +2 more sources
Development and application of a bioassay for follicle-stimulating hormone : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University [PDF]
, 2000 Follicle-stimulating hormone (FSH) is involved in the regulation and maintenance of vital reproductive processes, such as gametogenesis, follicular development and ovulation.
Young, Wayne
core
Activin receptor 2A and activin receptor 2B genes in chicken: effect on carcass traits
Journal of Applied Animal Research, 2015 Carcass traits are of immense importance in chicken as some parts of the carcass particularly breast muscle and legs are mostly preferred by the consumers with good market price while the remaining parts have a lower price. Carcass traits primarily depend on the growth of the birds, which are controlled by the candidate genes.
T. K. Bhattacharya +4 more
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Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary. [PDF]
PLoS ONE, 2010 Female germ cells are essential for organogenesis of the ovary; without them, ovarian follicles do not form and functional and structural characteristics of the ovary are lost.
Chia-Feng Liu +2 more
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Parkinson's Disease Patient‐Specific Striatum Organoids Show Hallmarks of Increased Inflammation
Movement Disorders, EarlyView.Abstract Background Dopaminergic neurons from the substantia nigra pars compacta project their axons into the dorsal striatum, forming the nigrostriatal pathway. In Parkinson's disease (PD), dopaminergic terminals degenerate in the striatum, leading to dopamine depletion, which in turn causes alterations in the basal ganglia circuits that are essential
Kyriaki Barmpa +11 more
wiley +1 more source
Mediators of Inflammation, 2015 Aims. To measure the expression of activin βA-subunit, activin IIA and IIB receptors, Smad4, Smad7, and follistatin in the liver and the liver and serum concentrations of mature activin-A and follistatin in normal rat following treatment with pegylated ...
Bassem Refaat +4 more
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