Results 101 to 110 of about 5,391 (252)
, 2021 This study explored the roles of activins and follistatin in colorectal cancers. Paired malignant and normal colonic tissues were collected from archived paraffin-embedded (n = 90 patients) alongside fresh (n = 40 patients) specimen cohorts.
Jamal Zekri (11717870) +14 more
core +1 more source
Integrative Zoology, EarlyView.① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li +16 more
wiley +1 more source
Journal of Immunology Research, 2014 The transforming growth factor-β (TGF-β) superfamily is a family of structurally related proteins that includes TGF-β, activins/inhibins, and bone morphogenic proteins (BMPs).
Belen Tirado-Rodriguez +3 more
doaj +1 more source
Review Article Activins and Follistatin in Chronic Hepatitis C and Its Treatment with Pegylated-Interferon-Based Therapy [PDF]
, 2020 Pegylated-interferon-based therapy for the treatment of chronic hepatitis C (CHC) is considered suboptimal as not all patients respond to the treatment and it is associated with several side effects that could lead to dose reduction and/or termination of
Esam Azhar +3 more
core
Allergy, EarlyView.Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider +48 more
wiley +1 more source
The role of activins during decidualisation of human endometrium
, 2006 Decidualisation of the endometrial stroma is critical to create a specialised environment for embryo implantation and trophoblast invasion; however, the mechanisms involved are poorly understood.
Jock K. FINDLAY +5 more
core +1 more source
Andrology, EarlyView.ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source
, 2018 Context: Clinical trials are evaluating the efficacy of inhibitors of the myostatin pathway in neuromuscular and metabolic diseases. Activins and follistatins are major regulators of the myostatin pathway, but their physiology in relation to metabolic ...
Perakakis N., Mougios V., Fatouros I., Siopi A., Draganidis D., Peradze N., Ghaly W., Mantzoros C.S.
core +1 more source
A comprehensive review of cancer‐induced cardiac wasting
British Journal of Pharmacology, EarlyView.Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena +5 more
wiley +1 more source
مجلة كلية الطبBackground: An ectopic pregnancy occurs when a fertilized egg implants itself—typically in one of the fallopian tubes—outside of the womb. Connecting the ovaries to the womb are tubes called fallopian tubes.
Hussein Al-Rkaby +2 more
doaj +1 more source