Results 91 to 100 of about 4,991 (262)

Diagnostic and prognostic values of serum activin-a levels in patients with acute respiratory distress syndrome

BMC Pulmonary Medicine, 2019
Background We aimed to evaluate whether serum activin-A levels are elevated and have any value in predicting severity and prognosis in acute respiratory distress syndrome (ARDS).
Jee-min Kim, Jung-Kyu Lee, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Sang-Min Lee   +10 more
doaj   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Potential roles for endometrial inhibins, activins and follistatin during human embryo implantation and early pregnancy [PDF]

, 2002
The human endometrium is a remarkably dynamic tissue, undergoing cycles of proliferation, differentiation and breakdown every 28 days. In preparation for embryo implantation, the endometrium differentiates or decidualizes, involving widespread ...
Rebecca L Jones, Findlay, Jock K., Jock K Findlay, Jones, Rebecca L., Salamonsen, Lois A., Lois A Salamonsen   +5 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Activins and prolactinoma development I: Sexual differences [PDF]

, 2018
Activins are members of the transforming growth factor beta (TGFβ) family of proteins. They are biologically active as dimers and, besides their known function on pituitary gonadotrophs, activins (A and B) also modulate lactotroph population, being ...
Diaz, Graciela Susana, Abeledo Machado, Alejandra Inés, Faraoni, Erika Yanil, Camilletti, María Andrea, Rulli, Susana Beatriz, Marcial López, Carla Agustina   +5 more
core  

Antiviral activity of bone morphogenetic proteins and activins [PDF]

, 2018
Understanding the control of viral infections is of broad importance. Chronic hepatitis C virus (HCV) infection causes decreased expression of the iron hormone hepcidin, which is regulated by hepatic bone morphogenetic protein (BMP)/SMAD signalling.
Webber, Caleb, Boninsegna, S, Sandor, C, Arezes, J, Vukicevic, Slobodan, Crowe, J, Crowe, John, Baddock, Hannah T., Giordani, Maria Teresa, Ryan, JD, Binder, M, Giannoulatou, E, Vukicevic, S, Martines, D, Armitage, AE, Chung, Raymond T., McHugh, Peter J., Al-Hourani, Kinda, Rehwinkel, J, Sandor, Cynthia, Webber, C, Baddock, HT, Owens, Benjamin M. J., Giannoulatou, Eleni, Al-Hourani, K, Babitt, Jodie L., Lawless, MW, Owens, BMJ, Drakesmith, Hal, Ryan, John D., Sun, Chia Chi, Fabris, Paolo, Boninsegna, Sara, Frankish, Jamie, Fusco, Dahlene N., Ramamurthy, N, Drakesmith, H, Rehwinkel, Jan, Klenerman, Paul, Armitage, Andrew E., Frankish, J, Martines, Diego, Klenerman, P, Fabris, P, Binder, Marco, Giordani, MT, McHugh, PJ, Lin, HY, Fusco, DN, Lawless, Matthew W., Eddowes, Lucy A., Lin, Herbert Y., Sun, CC, Chung, RT, Ramamurthy, Narayan, Chevaliez, S, Baddock, Hannah T, Babitt, JL, Armitage, Andrew, Chevaliez, Stephane, Arezes, Joao, Eddowes, LA   +61 more
core   +3 more sources

Retinal and choroidal angiogenesis: a review of new targets

International Journal of Retina and Vitreous, 2017
Retinal and choroidal neovascularization are a major cause of significant visual impairment, worldwide. Understanding the various factors involved in the accompanying physiopathology is vital for development of novel treatments, and most important, for ...
Thiago Cabral, Luiz Guilherme M. Mello, Luiz H. Lima, Júlia Polido, Caio V. Regatieri, Rubens Belfort, Vinit B. Mahajan   +6 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonist‐Based Agents and Body Composition: Filling More Gaps

Obesity, EarlyView.
ABSTRACT The last 2 decades have seen historic advances in the treatment of obesity. We are entering an era of defining obesity not by weight‐based outcomes but by changes in body composition. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are forming the platform for obesity treatments based on their high level of efficacy. Body composition can
Robert L. Dubin, Tierra N. Sanders, Hunter M. Schwab, Steven B. Heymsfield, Frank L. Greenway   +4 more
wiley   +1 more source

Inhibins and activins: Their roles in the adrenal gland and the development of adrenocortical tumors [PDF]

, 2012
The adrenal gland is composed of two separate endocrine tissues that control a multitude of bodily functions in their adaptation to external and internal stressors through hormone secretion. The functions of the adrenal gland are regulated by circulating,
Jong, Frank, Johannes Hofland, Hofland, Hans, Frank H. de Jong   +3 more
core   +1 more source