Results 41 to 50 of about 10,673,510 (116)

Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes [PDF]

, 2014
Aims/hypothesis: Impaired glucose uptake in skeletal muscle is an important contributor to glucose intolerance in type 2 diabetes. The aspartate protease, beta-site APP-cleaving enzyme 1 (BACE1), a critical regulator of amyloid precursor protein (APP ...
Hamilton, D. Lee, Montagut , Gemma, Meakin, Paul J., Susan M. Jalicy, Meakin, PJ, D. Lee Hamilton, Dawn Bestow, Bestow, D, Hamilton, DL, Montagut, G, Michael L. J. Ashford, Jalicy, Susan M., Findlay, John A., Jalicy, SM, Ashford, MLJ, Ashford, Michael L. J.; id_orcid, Montagut, Gemma, John A. Findlay, Gemma Montagut, Meakin, Paul J, Ashford, Michael L J, Bestow, Dawn, Findlay, John A, Jalicy, Susan M, Hamilton, David Lee, Findlay, JA, Paul J. Meakin   +26 more
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Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. [PDF]

, 2013
The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV). Eventually, in a tightly regulated process called egress, proteins of the PV and intracellular merozoite surface are modified by an essential parasite serine ...
Baker, David A, Strath Malcolm, Maria Penzo, David A Baker, Hackett Fiona, Penzo, Maria, Blackman, Michael J, Michael J Blackman, David A. Baker (122252), Christine R Collins, Fiona Hackett (27620), Christine R. Collins, Strath, Malcolm, Withers-Martinez, Chrislaine, David A. Baker, Michael J. Blackman, Malcolm Strath (411645), Withers-Martinez Chrislaine, Penzo Maria, Chrislaine Withers-Martinez, Malcolm Strath, Collins Christine R., Hackett, Fiona, Fiona Hackett, Chrislaine Withers-Martinez (27619), Baker David A., Collins, Christine R, Christine R. Collins (191982), Michael J. Blackman (192013), Blackman Michael J., Maria Penzo (411646)   +30 more
core   +1 more source

Moderate Physical Activity Increases the Expression of ADNP in Rat Brain

Activity-dependent neuroprotective protein (ADNP) is a neuroprotective protein essential for embryonic development, proper brain development, and neuronal plasticity.
Grazia Maugeri, Concetta Federico, Agata Grazia D’Amico, Giuseppe Musumeci, Salvatore Saccone, Velia D’Agata   +5 more
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Effects of 17β-oestradiol on rat detrusor smooth muscle contractility [PDF]

, 2009
The aim of this study was to investigate the effect of 17β-oestradiol (E2) on detrusor smooth muscle contractility and its possible neuroprotective role against ischaemic-like condition, which could arise during overactive bladder disease.
Keith L. Brain, Sgaragli, G, Giampietro Sgaragli, Pessina, F, Sgaragli, G., Pessina, F., Young, John, John S. Young, Valeri, A., Young, JS, Sgaragli, GIAN PIETRO, Valeri, A, Young, J. S., Aurora Valeri, Brain, K., Brain, K. L., Pessina, Federica, Federica Pessina, Brain, Keith; id_orcid, Brain, KL   +19 more
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Ubiquitin-proteasome dependent mitochondrial protein quality control [PDF]

, 2014
Dysfunctional mitochondria cause many neurodegenerative disorders and with aging in general, mechanisms of mitochondrial quality control are essential for cellular function.
Benischke, Anne-Sophie
core   +1 more source

ADNP is associated with immune infiltration and radiosensitivity in hepatocellular carcinoma for predicting the prognosis

, 2023
Background Hepatocellular carcinoma (HCC) is one of the most lethal diseases due to its high faculty of invasiveness and metastasis. Activity-dependent neuroprotective protein (ADNP) has been regarded as an oncogene in bladder cancer and ovarian cancer ...
Zeyuan Li, Honghua Peng, Xuan Wang, Zhangyan Du, Ganghua Zhang, Peiguo Cao, Bin Peng   +6 more
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Premature primary tooth eruption in cognitive/motor-delayed ADNP-mutated children

, 2017
: A major flaw in autism spectrum disorder (ASD) management is late diagnosis. Activity-dependent neuroprotective protein (ADNP) is a most frequent de novo mutated ASD-related gene. Functionally, ADNP protects nerve cells against electrical blockade.
Karmon, G., Gabet, Y., Gozes, I., M Pasmanik-Chor, Pasmanik-Chor, M., G Karmon, Giladi, E., I Gozes, A Van Dijck, R F Kooy, I Grigg, S Bedrosian-Sermone, Eger, M., Elpeleg, O., Grigg, I., E Cappuyns, M Eger, Y Gabet, Bedrosian-Sermone, S., Cappuyns, Elisa, E Giladi, Van Dijck, Anke, G Hacohen-Kleiman, O Elpeleg, Hacohen-Kleiman, G., Kooy, Frank   +25 more
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3',5'-Cyclic Adenosine Monophosphate- and Ca2+-Calmodulin-Dependent Endogenous Protein Phosphorylation Activity in Membranes of the Bovine Chromaffin Secretory Vesicles: Identification of Two Phosphorylated Components as Tyrosine Hydroxylase and Protein Kinase Regulatory Subunit Type II [PDF]

, 1983
: Membranes of the secretory vesicles from bovine adrenal medulla were investigated for the presence of the endogenous protein phosphorylation activity. Seven phosphoprotein bands in the molecular weight range of 250,000 to 30,000 were observed by means ...
Weber, W., Treiman, M., Gratzl, Manfred
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GABA(A) receptor phospho-dependent modulation is regulated by phospholipase C-related inactive protein type 1, a novel protein phosphatase 1 anchoring protein [PDF]

, 2004
GABA(A) receptors are critical in controlling neuronal activity. Here, we examined the role for phospholipase C-related inactive protein type 1 (PRIP-1), which binds and inactivates protein phosphatase 1alpha (PP1alpha) in facilitating GABA(A) receptor ...
Kanematsu, T, Terunuma, M, Jovanovic, JN, Jang, IS, Kittler, JT, Akaike, N, Nakayama, KI, Ryu, SH, Moss, SJ, Ha, SH, Hirata, M   +10 more
core  

ADNP exhibits methyltransferase activity in overexpression systems and modulates DNA and histone methylation

: Activity-Dependent Neuroprotective Protein (ADNP) is a putative transcription factor that differentially interacts with proteins involved in chromatin remodeling, thereby controlling neuronal differentiation.
Van Dijck, Anke, Kooy, R. Frank, Scott, Ayu, D' Incal, Claudio, Elinck, Ellen, Annear, Dale John, Van Rossem, Kirsten Esther, De Man, Kevin, Konings, Anthony, Cappuyns, Elisa   +9 more
core   +1 more source