Results 11 to 20 of about 127,480 (296)

Omadacycline for Acute Bacterial Skin and Skin-Structure Infections [PDF]

New England Journal of Medicine, 2019
Acute bacterial skin and skin-structure infections are associated with substantial morbidity and health care costs. Omadacycline, an aminomethylcycline antibiotic that can be administered once daily either orally or intravenously, is active against pathogens that commonly cause such infections, including antibiotic-resistant strains.In this double ...
O’Riordan, William, Green, Sinikka, Overcash, J. Scott, Puljiz, Ivan, Metallidis, Symeon, Gardovskis, J., Garrity-Ryan, Lynne, Das, Anita F., Tzanis, Evan, Eckburg, Paul B., Manley, Amy, Villano, Stephen A., Steenbergen, Judith N., Loh, Evan   +13 more
exaly   +7 more sources

Acute bacterial skin and skin structure infections: current perspective

Indian Journal of Dermatology, 2011
A skin and skin structure infection is a bacterial infection of skin and associated tissues. It may be complicated skin and skin structure infection or uncomplicated skin and skin structure infection. Recently, the Food and Drug Administration has called
Megha Shah, Hetal D Shah
doaj   +3 more sources

Omadacycline Oral Dosing and Pharmacokinetics in Community-Acquired Bacterial Pneumonia and Acute Bacterial Skin and Skin Structure Infection. [PDF]

Clin Drug Investig, 2022
Omadacycline, a first-in-class aminomethylcycline antibiotic, is approved in the USA as intravenous (IV) and/or oral therapy for treatment of adults with community-acquired bacterial pneumonia (CABP) or acute bacterial skin and skin structure infections (ABSSSI). Phase 1 and 3 studies indicate that omadacycline dose adjustments are not required for any
Leviton IM, Amodio-Groton M.
europepmc   +4 more sources

Oritavancin for acute bacterial skin and skin structure infections. [PDF]

Expert Opin Pharmacother, 2015
Inpatient treatment of acute bacterial skin and skin structure infections (ABSSSIs) exerts a significant economic burden on the healthcare system. Oritavancin is a concentration-dependent, rapid bactericidal agent approved for the treatment of ABSSSIs.
Messina JA, Fowler VG, Corey GR.
europepmc   +7 more sources

Diabetes and acute bacterial skin and skin structure infections [PDF]

Diabetes Research and Clinical Practice, 2021
Acute bacterial skin and skin structures infections (ABSSSIs) are associated with high morbidity, costs and mortality in patients with diabetes mellitus. Their appropriate management should include several figures and a well-organized approach. This review aims to highlight the interplay between diabetes and ABSSSIs and bring out the unmet clinical ...
Falcone M, Meier JJ, Marini MG, Caccialanza R, Aguado JM, Del Prato S, Menichetti F.   +6 more
openaire   +4 more sources

Outpatient care concept and potential inpatient cost savings associated with the administration of dalbavancin – A real-world data and retrospective cost analysis

Journal of Infection and Public Health, 2023
Background: The treatment of acute bacterial skin and skin structure infections (ABSSSI) usually involves intravenous (i.v.) antibiotics requiring hospitalisation and increasing hospital costs.
Christoph T. Baltin, Carolin Wulf, Robert Rongisch, Clara Lehmann, Sebastian Wingen-Heimann, Nicole Eisenmenger, Jennifer Bonn, Mario Fabri, Esther von Stebut, Oliver A. Cornely, Florian Kron   +10 more
doaj   +1 more source

Columnaris disease in fish: a review with emphasis on bacterium-host interactions [PDF]

, 2013
Flavobacterium columnare (F. columnare) is the causative agent of columnaris disease. This bacterium affects both cultured and wild freshwater fish including many susceptible commercially important fish species. F. columnare infections may result in skin
Bossier, Peter, Declercq, Annelies, Decostere, Annemie, Haesebrouck, Freddy, Van Den Broeck, Wim   +4 more
core   +3 more sources

Successful Treatment of Acute Prostatitis Caused by Multidrug-Resistant Escherichia coli With Tigecycline Monotherapy [PDF]

, 2020
We present a successful treatment, with tigecycline monotherapy, of acute prostatitis caused by multidrug-resistant Escherichia coli harboring an NDM-1 carbapemenase along with a CMY-2 cephalosporinase and a TEM ...
Babouee Flury, Baharak, Buetti, Niccolo, Casanova, Carlo, Furrer, Hansjakob, Jent, Philipp, Livermore, David M, Lo Priore, Elia, Pelzer, Niklas   +7 more
core   +2 more sources

Dalbavancin for the treatment of acute bacterial skin and skin structure infections [PDF]

Expert Opinion on Pharmacotherapy, 2015
Acute bacterial skin and skin structure infections (ABSSSI) have increased in incidence and severity. The involvement of resistant organisms, particularly methicillin-resistant Staphylococcus aureus, presents additional challenges. The lipoglycopeptide dalbavancin has a prolonged half-life, high protein binding, and excellent tissue levels which led to
Sheena, Ramdeen, Helen W, Boucher
openaire   +2 more sources

In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection [PDF]

, 2017
Pseudomonas aeruginosa is an opportunistic and frequently drug-resistant pulmonary pathogen especially in cystic fibrosis sufferers. Recently, the frog skin-derived antimicrobial peptide (AMP) Esc(1-21) and its diastereomer Esc(1-21)-1c were found to ...
Chen, Chen, Di, Y. Peter, Mangoni, Maria Luisa   +2 more
core   +1 more source