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Acute bacterial skin and skin-structure infections (ABSSSI) is defined in 2013 by the US Food and Drug Administration as a bacterial cellulitis/erysipelas, major skin abscesses, and wound infections.
Erni Juwita Nelwan +3 more
doaj +2 more sources
Delafloxacin: A Review in Acute Bacterial Skin and Skin Structure Infections [PDF]
The global spread of antibacterial-resistant strains, especially methicillin-resistant Staphylococcus aureus (MRSA) for acute bacterial skin and skin structure infections (ABSSSIs), has driven the need for novel antibacterials. Delafloxacin [Quofenix™ (EU); Baxdela® (USA)], a new fluoroquinolone (FQ), has a unique chemical structure that enhances its ...
openaire +2 more sources
Hydrogen Peroxide Wound Irrigation in Orthopaedic Surgery. [PDF]
As the burden of deep hardware infections continues to rise in orthopaedics, there is increasing interest in strategies for more effective debridement of colonized tissues and biofilm.
Hansen, Erik Nathan, Lu, Min
core +1 more source
Introduction The prevalence of acute bacterial skin and skin structure infections (ABSSSIs) continues to increase. Bloodstream infection (BSI) is a severe secondary complication of ABSSSI.
Michael J. Rybak +6 more
doaj +1 more source
Impact of Outpatient vs Inpatient ABSSSI Treatment on Outcomes: A Retrospective Observational Analysis of Medical Charts Across US Emergency Departments [PDF]
Background The objective of this study was to characterize treatment of patients with acute bacterial skin and skin structure infections (ABSSSIs) and describe the association between hospital admission and emergency department (ED) visits or ...
Bookstaver, P. Brandon +12 more
core +3 more sources
Ceftaroline-related acute eosinophilic pneumonia
Ceftaroline fosamil is a novel 5th generation broad-spectrum oxyimino-cephalosporin with activity against Staphylococcus aureus, including methicillin-resistant S.
Zaw Min +4 more
doaj +1 more source
Borrelia burgdorferi Manipulates Innate and Adaptive Immunity to Establish Persistence in Rodent Reservoir Hosts. [PDF]
Borrelia burgdorferi sensu lato species complex is capable of establishing persistent infections in a wide variety of species, particularly rodents. Infection is asymptomatic or mild in most reservoir host species, indicating successful co-evolution of ...
Baumgarth, Nicole, Tracy, Karen E
core +1 more source
Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid [PDF]
BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice.
A Loeffler +29 more
core +5 more sources
Early Endpoints for Acute Bacterial Skin and Skin Structure Infections [PDF]
In this issue of the journal, [Friedland et al.][1] ([4][2]) present a retrospective analysis of the two CANVAS trials ([3][3]), employing the newer endpoints from the U.S. Food and Drug Administration (FDA) ([7][4]).
openaire +2 more sources
Infectious agents and inflammation. The role of microbiota in autoimmune arthritis [PDF]
In higher vertebrates, mucosal sites at the border between the internal and external environments, directly interact with bacteria, viruses, and fungi.
D'Amelio, Raffaele +2 more
core +2 more sources

