Sex Differences in rt-PA Utilization at Hospitals Treating Stroke: The National Inpatient Sample. [PDF]
, 2017 BACKGROUND AND PURPOSE: Sex and race disparities in recombinant tissue plasminogen activator (rt-PA) use have been reported. We sought to explore sex and race differences in the utilization of rt-PA at primary stroke centers (PSCs) compared to non-PSCs ...
Albright, Karen C +7 more
core +2 more sources
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Advanced Biology, EarlyView.Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
The concentration of homocysteine in patients after ischemic brain stroke and vascular dementia
Journal of Health Sciences, 2011 Introduction: The aim of this study is to examine whether moderate hiperhomocysteinemia is an independent risk factor for cerebral infarction. Methods: We have measured homocysteine levels in 50 patients with ischemic stroke during acute phase and ...
Nafija Serdarević +2 more
doaj +1 more source
Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) [PDF]
, 2009 <p><b>Background and Purpose:</b> The optimal management of blood pressure (BP) in acute stroke remains unclear. For ischemic stroke treated with intravenous thrombolysis, current guidelines suggest pharmacological intervention if ...
Ahmed, N. +4 more
core +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Systemic infections after acute stroke [PDF]
, 2008 After an acute stroke, systemic infection can complicate the recovery process and lead to a worse clinical outcome, including a higher risk of mortality.
Damian Jenkinson +11 more
core +1 more source
Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses
Advanced Healthcare Materials, EarlyView.Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri +6 more
wiley +1 more source
The Role of Diabetes Mellitus, Dyslipidemia, and Smoking as Risk Factors in Acute Ischemic Stroke Incidence Among Hypertensive Subject [PDF]
, 2016 Introduction: Stroke is a leading cause of disability in the elderly, and the second leading cause of the death worldwide. This study aims to analyze the role of risk factors for diabe- tes mellitus (DM), dyslipidemia, and smoking in hypertensive ...
Nurlia, N. (Nurlia)
core
The future of ischemic stroke: flow from prehospital neuroprotection to definitive reperfusion. [PDF]
, 2014 Recent advances in ischemic stroke enable a seamless transition of the patient flow from the prehospital setting to definitive reperfusion, without the arbitrary separation of therapeutic phases of ischemia based on time alone.
Ip, Hing Lung, Liebeskind, David S
core +1 more source
Elevated Total Homocysteine Levels in Acute Ischemic Stroke Are Associated With Long-Term Mortality
Stroke, 2015 Background and Purpose— Total homocysteine (tHcy) levels are associated with secondary vascular events and mortality after stroke. The aim of this study was to investigate whether tHcy levels in the acute phase of a stroke contribute to the recurrence of
Zhihong Shi +8 more
semanticscholar +1 more source