Results 111 to 120 of about 375,624 (302)

Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: individual-patient-data meta-analysis of randomized trials [PDF]

, 2017
Background: The recommended maximum age and time window for intravenous alteplase treatment of acute ischemic stroke differs between the Europe Union and United States.
Colin Baigent, Danilo Toni, Erich Bluhmki, Geoffrey A Donnan, Geoffrey Cohen, George Howard, Gregory Albers, Gregory del Zoppo, James C Grotta, Jean-Marc Olivot, Joanna M Wardlaw, Jonathan Emberson, Kazunori Toyoda, Kennedy R Lees, Lisa Blackwell, Maarten G Lansberg, Mark Parsons, Markku Kaste, Masatoshi Koga, Nils Wahlgren, null null, Patrick Lyden, Peter AG Sandercock, Richard I Lindley, Rüdiger von Kummer, Stephen M Davis, Thomas Brott, Werner Hacke, William N Whiteley   +28 more
core   +5 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem Cell Trial of Recovery EnhanceMent After Stroke (STEMS) Pilot Randomized, Controlled Trial (ISRCTN 16784092) [PDF]

, 2006
Background and Purpose - Loss of motor function is common after stroke and leads to significant chronic disability. Stem cells are capable of self-renewal and of differentiating into multiple cell types, including neurones, glia, and vascular cells.
Bath, Philip M.W., Dennis, Martin S., Gray, Laura J., Russell, Nigel, Sprigg, Nikola, Walker, Marion F., Willmot, Mark, Zhao, Lian   +7 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Current endovascular treatment of acute ischemic stroke

Вестник хирургии имени И.И. Грекова
Acute ischemic stroke is one of the leading causes of death and long-term disability. For a long time, intravenous thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) has been the only method of treating patients with acute ischemic ...
D. V. Kandyba, K. V. Babichev
doaj   +1 more source

A study of factors delaying hospital arrival and predictors of mortality in patients presenting to emergency department with stroke: A developing state scenario [PDF]

, 2010
Background: Thrombolytic therapy for acute ischemic stroke has recently become available in India but its success depends on initiating the treatment in the narrow therapeutic time window.
Chandra, Subhash, Khan, Mudassir Azeez, Nagaraja, Vinayak, Sankapithilu, Ganraj Bhat   +3 more
core   +1 more source

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke [PDF]

, 2016
BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.
Albers, Gregory W., Amarenco, Pierre, Bornstein, Natan M., Canhão, Patrícia, Caplan, Louis R., Donnan, Geoffrey A., Ferro, José M., Hennerici, Michael G., Labreuche, Julien, Lavallée, Philippa C., Molina, Carlos, org Steering Committee, T. I. A. r. e. g. i. s. t. r. y., Rothwell, Peter M., Sissani, Leila, Steg, Philippe Gabriel, Toni, Danilo, Touboul, Pierre Jean, Uchiyama, Shinichiro, Vicaut, Éric, Wong, Lawrence K. S., Školoudík, David   +20 more
core   +2 more sources

Unilateral Ankle‐Foot Exoneuromusculoskeleton with Balance‐Sensing Feedback for Self‐Help Telerehabilitation after Stroke

Advanced Robotics Research, EarlyView.
This study introduces a hybrid robot that integrates mechanical assistance by musculoskeletons (i.e., soft pneumatic muscle with rigid exoskeletal extensions), neuromuscular electrical stimulation, and vibrotactile feedback in a lightweight wearable mechatronic complex applicable to the paretic ankle–foot poststroke for gait restoration. The system can
Fuqiang Ye, Wei Rong, Waiming Li, Kwok‐Ting Wong, Man‐Kit Pang, Hon‐Wah Wai, Lilly Li, Zicong Hong, Song Guo, Zong‐Hao Ma, Yongping Zheng, Ming Zhang, Nicholas Chow, Jianing Zhang, Xiaoling Hu, Fei Chen, Waisang Poon   +16 more
wiley   +1 more source

Predictors for cerebral edema in acute ischemic stroke treated with intravenous thrombolysis [PDF]

, 2017
Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction.
Ahmed, Niaz, Azevedo, Elsa, Dawson, Jesse, Egido, Jose A., Falcou, Anne, Ford, Gary A., Holmin, Staffan, Mikulik, Robert, Ollikainen, Jyrki, Thorén, Magnus, Wahlgren, Nils   +10 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source