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Nature Reviews Disease Primers, 2021 Acute kidney injury (AKI) is defined by a sudden loss of excretory kidney function. AKI is part of a range of conditions summarized as acute kidney diseases and disorders (AKD), in which slow deterioration of kidney function or persistent kidney dysfunction is associated with an irreversible loss of kidney cells and nephrons, which can lead to chronic ...
J. Kellum +5 more
semanticscholar +6 more sources
Survival and recovery modeling of acute kidney injury in critically ill adults [PDF]
SAGE Open Medicine, 2022 Objectives: Acute kidney injury is common among the critically ill. However, the incidence, medication use, and outcomes of acute kidney injury have been variably described.
Todd N Brothers +5 more
doaj +3 more sources
The Effects of Baicalin on Myoglobinuric Acute Renal Failure in Rats [PDF]
Balkan Medical Journal, 2018 Background: Myoglobinuric acute kidney injury is a uremic syndrome that develops due to damage of skeletal muscle. Free radicals and nitric oxide play an important role in the pathogenesis of myoglobinuric acute kidney injury.
Özlem Yalçınkaya Yavuz1 +3 more
doaj +4 more sources
Clinical Medicine, 2009 The term acute kidney injury (AKI) has now replaced the term acute renal failure (ARF) and represents the entire spectrum of the latter. It is best characterised by a rapid decline in kidney function over hours to weeks with the retention of nitrogenous waste products and creatinine.
M. Rosner
semanticscholar +4 more sources
Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study [PDF]
, 2008 Introduction: The purpose of this study was to determine the incidence, time course, and outcome of acute kidney injury after major burns and to evaluate the impact of possible predisposing factors ( age, gender, and depth and extent of injury) and the ...
Ingrid Steinvall +2 more
openalex +5 more sources
A Clinically Applicable Approach to Continuous Prediction of Future Acute Kidney Injury
Nature, 2019 The early prediction of deterioration could have an important role in supporting healthcare professionals, as an estimated 11% of deaths in hospital follow a failure to promptly recognize and treat deteriorating patients1.
Nenad Tomašev +26 more
semanticscholar +3 more sources
Acute kidney injury in burns: a story of volume and inflammation [PDF]
, 2008 Acute kidney injury occurs in approximately one-quarter to one-third of patients with major burn injury. Apart from the usual suspects – such as older age, severity of burn injury, sepsis and multiple organ dysfunction – volume overload probably has an ...
Kirsten Colpaert, Eric A. J. Hoste
openalex +5 more sources
Biomarkers in acute kidney injury [PDF]
Annals of Intensive CareAbstractAcute kidney injury (AKI) is a multifactorial syndrome with a high risk of short- and long-term complications as well as increased health care costs. The traditional biomarkers of AKI, serum creatinine and urine output, have important limitations.
Marlies Ostermann +5 more
openaire +4 more sources
BioMed Research International, 2015 Acute kidney injury (AKI) is a frequent and serious clinical condition which is associated with poor outcomes, including high mortality rate. Classically, it was considered as an acute condition, potentially reversible with full restitution if patient survives the acute phase of the disease.
Raúl Lombardi +3 more
+16 more sources
Revista da Associação Médica Brasileira, 2020 Acute renal failure definitions have changed dramatically over the last 5 to 10 years as a result of criteria established through the following consensus statements/organizations: RIFLE (Risk, Injury, Failure, Loss of function, End stage renal disease), AKIN (Acute Kidney Injury Network), and KDIGO (Kidney Disease: Improving Global Outcomes).
Carlos V.R. Brown +2 more
+9 more sources