Results 41 to 50 of about 884,542 (406)

Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Single nucleus RNA sequencing revealed gene expression changes during repair after acute kidney injury. We describe a small population of proximal tubule cells that fail to repair (FR-PTCs).
Y. Kirita, Haojia Wu, Kohei Uchimura, Parker C. Wilson, B. Humphreys   +4 more
semanticscholar   +1 more source

Targeting ferroptosis in acute kidney injury

Cell Death and Disease, 2022
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality. As a form of programmed cell death (PCD), ferroptosis could be considered as a process of iron accumulation and enhanced lipid peroxidation.
Lihua Ni, C. Yuan, Xiaoyan Wu
semanticscholar   +1 more source

Obesity, Acute Kidney Injury, and Mortality in Critical Illness [PDF]

, 2016
Objectives: Although obesity is associated with risk for chronic kidney disease and improved survival, less is known about the associations of obesity with risk of acute kidney injury and post acute kidney injury mortality.
Celi, Leo Anthony G., Chen, Ken P., Danziger, John, Feng, Mengling, Lee, Joonwu, Mark, Roger G, Mukamal, Kenneth J.   +6 more
core   +1 more source

Nomenclature and diagnostic criteria for acute kidney injury – 2020 consensus of the Taiwan AKI-task force

Journal of the Formosan Medical Association, 2022
Acute kidney injury (AKI) is a common syndrome that has a significant impact on prognosis in various clinical settings. To evaluate whether new evidence supports changing the current definition/classification/staging systems for AKI suggested by the ...
Shao-Yu Yang, Terry Ting-Yu Chiou, Chih-Chung Shiao, Hugo You-Hsien Lin, Ming-Jen Chan, Che-Hsiung Wu, Chiao-Yin Sun, Wei-Jie Wang, Yen-Ta Huang, Vin-Cent Wu, Yung-Chang Chen, Ji-Tsung Fang, Shang-Jyh Hwang, Heng-Chih Pan   +13 more
doaj  

Acute kidney injury, mortality, length of stay, and costs in hospitalized patients.

Journal of the American Society of Nephrology, 2005
The marginal effects of acute kidney injury on in-hospital mortality, length of stay (LOS), and costs have not been well described. A consecutive sample of 19,982 adults who were admitted to an urban academic medical center, including 9210 who had two or
G. Chertow, E. Burdick, Melissa M. Honour, J. Bonventre, D. Bates   +4 more
semanticscholar   +1 more source

Drug-Induced Acute Kidney Injury

American Society of Nephrology. Clinical Journal, 2022
Medications are a common cause of AKI, especially for patients admitted to hospital wards and the intensive care unit. Although drug-related kidney injury occurs through different mechanisms, this review will focus on three specific types of ...
M. Perazella, M. Rosner
semanticscholar   +1 more source

Acute kidney injury and chronic kidney disease as interconnected syndromes.

New England Journal of Medicine, 2014
For more than 40 years, nephrologists have classified diminished kidney function as two distinct syndromes — acute and chronic kidney failure. Whereas chronic kidney disease was recognized in the 19th century, acute renal dysfunction became evident ...
L. Chawla, P. Eggers, R. Star, P. Kimmel
semanticscholar   +1 more source

Acute and chronic kidney disease in elderly patients with hip fracture: prevalence, risk factors and outcome with development and validation of a risk prediction model for acute kidney injury [PDF]

, 2017
Background Hip fracture is a common injury in older people with a high rate of postoperative morbidity and mortality. This patient group is also at high risk of acute kidney injury (AKI) and chronic kidney disease (CKD), but little is known of the ...
A Ishani, AS Levey, Christine J. Porter, Christopher G. Moran, CJ Porter, CY Hsu, D Nitsch, DE Rifkin, DJ Canty, E Bartha, EB Wilson, ER DeLong, F Borgstrom, F Hu, GS Collins, HM Hodkinson, Iain K. Moppett, ID Bucaloiu, IK Moppett, IK Moppett, IK Moppett, Irene Juurlink, J Karres, JA Kanis, Jessica Nightingale, JP Lafrance, Kidney Disease, M Kuhn, Mark A. J. Devonald, MD Wiles, MJ Maxwell, MJ Parker, PC Austin, PN Baker, PR Rushton, R Bellomo, R Core Team, R Wald, RL Mehta, S Anderson, S Kheterpal, S Kheterpal, S Kundu, S Uchino, SA Frost, SG Coca, SG Coca, SG Coca, SI Ylinenvaara, SJ Bennet, SM White, SM White, SM White, XL Griffin   +53 more
core   +1 more source

COVID-19–Related Glomerulopathy: A Report of 2 Cases of Collapsing Focal Segmental Glomerulosclerosis [PDF]

, 2020
Coronavirus disease 19 (COVID-19), an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with acute kidney injury, presumably due to acute tubular injury.
Alhashimi, Fatema, Berhanu, Kabaye, Bichu, Prasad, Hu, Yanglin, Khanna, Siddharth, Magoon, Sandeep, Malhotra, Varun   +6 more
core   +2 more sources

Identification of Maltase Glucoamylase as a Biomarker of Acute Kidney Injury in Patients with Cirrhosis

Critical Care Research and Practice, 2019
Background. Acute kidney injury (AKI) is a frequent complication of decompensated cirrhosis with increased mortality. Traditional biomarkers such as serum creatinine are not sensitive for detecting injury without functional change.
Linda Awdishu, Shirley Tsunoda, Michelle Pearlman, Chanthel Kokoy-Mondragon, Majid Ghassemian, Robert K. Naviaux, Heather M. Patton, Ravindra L. Mehta, Bhavya Vijay, Satish P. RamachandraRao   +9 more
doaj   +1 more source