Results 21 to 30 of about 1,516,904 (247)
An Intelligent Decision Support System for Leukaemia Diagnosis using Microscopic Blood Images [PDF]
, 2015 This research proposes an intelligent decision support system for acute lymphoblastic leukaemia diagnosis from microscopic blood images. A novel clustering algorithm with stimulating discriminant measures (SDM) of both within- and between-cluster scatter Nauman Aslam (13538530), Hossain, Alamgir, Peng Lim, Chee, Hossain, Mohammed Alamgir, Mohammed Alamgir Hossain (16653492), Zhang, Li, Greystoke, Brigit, Stephen Todryk (65497), Chee Peng Lim (11979216), Worawut Srisukkham (16657476), Srisukkham, Worawut, Todryk, Stephen, Brigit Greystoke (420963), Aslam, Nauman, Lim, Chee Peng, Siew Chin Neoh (16671366), Chin Neoh, Siew, Neoh, Siew Chin, Li Zhang (8200) +18 morecore +1 more sourceA Review of Acute and Long-Term Neurological Complications Following Haematopoietic Stem Cell Transplant for Paediatric Acute Lymphoblastic Leukaemia
Frontiers in Pediatrics, 2021 Despite advances in haematopoietic stem cell transplant (HSCT) techniques, the risk of serious side effects and complications still exists. Neurological complications, both acute and long term, are common following HSCT and contribute to significant ...Melissa Gabriel, Bianca A. W. Hoeben, Bianca A. W. Hoeben, Hilde Hylland Uhlving, Olga Zajac-Spychala, Anita Lawitschka, Dorine Bresters, Marianne Ifversen +7 moredoaj +1 more sourceA dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug l-asparaginase [PDF]
, 2009 l-Asparaginase is a key therapeutic agent for treatment of childhood acute lymphoblastic leukemia (ALL). There is wide individual variation in pharmacokinetics, and little is known about its metabolism.Vaskar Saha, Krishnan, S., Holland, Mark, Colin Watts, Mark Holland, Holland, M., Liu, JiZhong, Ariffin, Hany, Bates, P.A., Marcin Krol, Paul A. Bates, Moss, Catherine X., Patel, N., Essink, M., Patel, Naina, Clare Dempsey, Krishnan, Shekhar, van Delft, Frederik W., Watts, Colin, Carly Leighton, Leighton, Carly, Eden, T.O.B., Moss, C.X., Offman, Marc N., JiZhong Liu, Dempsey, Clare, Seema Alexander, Hany Ariffin, Bates, Paul A., Dempsey, C., Eden, Tim O B, Alexander, S., van Delft, F.W., Frederik W. van Delft, Watts, C., Offman, M.N., Saha, V., Leighton, C., Eden, Tim O.B., Saha, Vaskar; id_orcid, Shekhar Krishnan, Monika Essink, Saha, Vaskar, Krol, Marcin, Ariffin, H., Tim O.B. Eden, Naina Patel, Alexander, Seema, Catherine X. Moss, Krol, M., Marc N. Offman, Liu, J.Z., Essink, Monika, Van Delft, Frederik W, Offman, Marc N, Bates, Paul A, Moss, Catherine X, Dempsey, Clare E +57 morecore +1 more sourceInduction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993 [PDF]
, 2005 The international acute lymphoblastic leukemia (ALL) study was designed to prospectively define the optimal therapy for adults 60 years of age or younger with newly diagnosed ALL.Burnett, Alan Kenneth, Franklin, IM, Rowe, Jacob M., Richards, SM, Litzow, Mark R., Wiernik, P.H., Tallman, Martin S., Rowe, JM, Prentice, H. Grant, Goldstone, Anthony H., Wiernik, PH, Litzow, M.R., Litzow, MR, Ciobanu, N, Ciobanu, N., Prentice, HG, Durrant, J., Richards, Susan M., Durrant, J, Lazarus, H.M., Goldstone, A.H., Chopra, R, Lazarus, Hillard M., Wiernik, Peter H., Ciobanu, Niculae, Rowe, J.M., Tallman, MS, Durrant, Jill, Chopra, R., Lazarus, HM, Burnett, AK, Burnett, A.K., Buck, Georgina, Buck, G., Franklin, Ian M., Chopra, Raj, Goldstone, AH, Prentice, H.G., Richards, S.M., Tallman, M.S., Buck, G, Franklin, I.M. +41 morecore +1 more sourceAcute B lymphoblastic leukaemia‐propagating cells are present at high frequency in diverse lymphoblast populations
EMBO Molecular Medicine, 2012 Leukaemia‐propagating cells are more frequent in high‐risk acute B lymphoblastic leukaemia than in many malignancies that follow a hierarchical cancer stem cell model.Klaus Rehe, Kerrie Wilson, Simon Bomken, Daniel Williamson, Julie Irving, Monique L. den Boer, Martin Stanulla, Martin Schrappe, Andrew G. Hall, Olaf Heidenreich, Josef Vormoor +10 moredoaj +1 more sourceIn vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]
, 2012 Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.zur Stadt, Udo, Groiss, Volker, Schneider, Katja, Renier J Brentjens, Nadia Terziyska, Harald Ehrhardt, Jeremias, I., Brentjens, Renier J., Farkasova, K., Katja Schneider, Volker Groiss (106787), Katarina Farkasova (106794), Ehrhardt, Harald, Wagner, E., Renier J. Brentjens (106801), Quintanilla-Martinez, Leticia, Martin Horstmann (45040), Ehrhardt, H., Ernst Wagner (60760), Wagner, Ernst, Leticia Quintanilla-Martinez (33277), Terziyska, N., Katja Schneider (106791), Horstmann, M., Brentjens, R.J., Catarina Castro Alves, Quintanilla-Martinez, L., Zur Stadt, U., Horstmann, Martin, Schneider, K., Ogris, M., Manfred Ogris, Alves, C.C., Nadia Terziyska (106777), Terziyska, Nadia, Jeremias, Irmela, Groiss, V., Irmela Jeremias (106806), Volker Groiss, Udo zur Stadt, Martin Horstmann, Farkasova, Katarina, Ernst Wagner, Irmela Jeremias, Ogris, Manfred, Udo zur Stadt (106803), Catarina Castro Alves (106783), Manfred Ogris (60759), Castro Alves, Catarina, Katarina Farkasova, Leticia Quintanilla-Martinez, Harald Ehrhardt (106798) +51 morecore +2 more sourcesFLT3 mutations in Early T-Cell Precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors [PDF]
, 2013 Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) has been identified as high-risk subgroup of acute T-lymphoblastic leukemia (T-ALL) with a high rate of FLT3-mutations in adults.Hartmut Döhner (276603), Hofmann, Wolf-Karsten, Christian Brandts, Ulrich Dührsen, Eckhard Thiel (66496), Mochmann, Liliana H., Burmeister, Thomas, Lars Fransecky, Neumann, Martin, Döhner, Hartmut, Eckhard Thiel, Nicola Gökbuget, Claudia D Baldus, Martin Griesshammer (276602), Rainer Haas (81562), Sartangi, Nasrin Farhadi, Martin Neumann (276593), Gerhard Ehninger, Schwartz, Stefan, Dieter Hoelzer, Stefan Schwartz (276600), Nicola Gökbuget (276599), Olga Blau, Isabelle Bartram, Bartram, Isabelle, Thiel, Eckhard, Liliana H Mochmann, Wolf-Karsten Hofmann, Thomas Burmeister, Martin Neumann, Martin Griesshammer, Sandra Heesch (276598), Heesch, Sandra, Haas, Rainer, Rainer Haas, Schlee, Cornelia, Fransecky, Lars, Ulrich Dührsen (106782), Griesshammer, Martin, Christian Brandts (276601), Lars Fransecky (276595), Ebru Coskun, Claudia D. Baldus (66494), Isabelle Bartram (276596), Wolf-Karsten Hofmann (66497), Ehninger, Gerhard, Brandts, Christian Hubertus, Baldus, Claudia, Gerhard Ehninger (106788), Dührsen, Ulrich, Hoelzer, Dieter, Cornelia Schlee, Dieter Hoelzer (551), Cornelia Schlee (105296), Ebru Coskun (276594), Gökbuget, Nicola, Sandra Heesch, Liliana H. Mochmann (105294), Hartmut Döhner, Nasrin Farhadi Sartangi, Nasrin Farhadi Sartangi (276597), Thomas Burmeister (276604), Stefan Schwartz, Coskun, Ebru, Olga Blau (276605), Blau, Olga +65 morecore +2 more sources
