Results 41 to 50 of about 4,781,689 (344)

A retrospective analysis of honey bee (Apis mellifera) pesticide toxicity data.

PLoS ONE, 2022
Current USEPA ecological risk assessments for pesticide registration include a determination of potential risks to bees. Toxicity data are submitted to support these assessments and the USEPA maintains a large database containing acute and chronic ...
Frank T Farruggia, Kristina Garber, Christine Hartless, Kristin Jones, Lee Kyle, Nicholas Mastrota, Joseph P Milone, Sujatha Sankula, Keith Sappington, Katherine Stebbins, Thomas Steeger, Holly Summers, Pamela G Thompson, Michael Wagman   +13 more
doaj   +1 more source

Study of Acute Toxicity of a New Veterinary Drug for Inttrammary Introduction [PDF]

, 2018
Preclinical studies of veterinary medicinal products are important and compulsory studies in the development of new dosage forms. The aim of preclinical research is to determine the toxic effect and therapeutic efficacy of the test substance-the future ...
Polova, Z. (Zhanna)
core  

Galleria mellonella (greater wax moth) larvae as a model for antibiotic susceptibility testing and acute toxicity trials

BMC Research Notes, 2017
BackgroundInfectivity trials and toxicity testing in rodents are important prerequisites to the use of compounds in man. However, trials in rats and mice are expensive and there are ethical considerations.
K. Ignasiak, A. Maxwell
semanticscholar   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Acute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ tracking

Radiation Oncology, 2008
Background To report acute and late toxicity in prostate cancer patients treated by dose escalated intensity-modulated radiation therapy (IMRT) and organ tracking.
Behrensmeier Frank, Madlung Axel, Tille Jan, Bigler Roland, Manser Peter, Vetterli Daniel, Vock Jacqueline, Ghadjar Pirus, Mini Roberto, Aebersold Daniel M   +9 more
doaj   +1 more source

Acute toxicity and genotoxicity of silver nanoparticle in rats

PLoS ONE, 2017
Objective The potential risk of a nanoparticle as a medical application has raised wide concerns, and this study aims to investigate silver nanoparticle (AgNP)-induced acute toxicities, genotoxicities, target organs and the underlying mechanisms. Methods
Hairuo Wen, Mo Dan, Ying Yang, Jianjun Lyu, Anliang Shao, Xiang Cheng, Liang Chen, Liming Xu   +7 more
semanticscholar   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

A comparative study of hydrophilic phosphine hexanuclear rhenium cluster complexes’ toxicity [PDF]

, 2017
Octahedral rhenium cluster compound Na2H8[{Re6Se8}(P(C2H4CONH2)(C2H4COO)2)6] has recently emerged as a very promising X-ray contrast agent for biomedical applications.
Alekseev, Alexander Y., Brylev, Konstantin A., Efremova, Olga A., Gulyaeva, Marina A., Ivanov, Anton A., Krasilnikova, Anna A., Kurskaya, Olga G., Mironov, Yuri V., Poveshchenko, Alexander F., Pozmogova, Tatiana N., Shestopalov, Alexander M., Shestopalov, Michael A., Shestopalova, Lidiya V., Solovieva, Anastasiya O.   +13 more
core   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

A Mechanism-based QSTR Model for Acute to Chronic Toxicity Extrapolation: A Case Study of Antibiotics on Luminous Bacteria

Scientific Reports, 2017
The determination of the chronic toxicity is time-consumed and costly, so it’s of great interest to predict the chronic toxicity based on acute data. Current methods include the acute to chronic ratios (ACRs) and the QSTR models, both of which have some ...
Dali Wang, Yue Gu, Min Zheng, Wei Zhang, Zhifen Lin, Ying Liu   +5 more
doaj   +1 more source