Results 11 to 20 of about 96,079 (210)

Evolution of acyl-substrate recognition by a family of acyl-homoserine lactone synthases. [PDF]

PLoS ONE, 2014
Members of the LuxI protein family catalyze synthesis of acyl-homoserine lactone (acyl-HSL) quorum sensing signals from S-adenosyl-L-methionine and an acyl thioester.
Quin H Christensen, Ryan M Brecht, Dastagiri Dudekula, E Peter Greenberg, Rajesh Nagarajan   +4 more
doaj   +7 more sources

Production of N -acyl homoserine lactones by the sponge-associated marine actinobacteria Salinispora arenicola and Salinispora pacifica

, 2017
The structures of acyl homoserine lactone (AHL) compounds and their quantification were accomplished using an integrated liquid chromatography-mass spectrometry approach.
Utpal Bose (534252), Amitha K. Hewavitharana (17220499), Catharine A. Ortori (17220502), Mark P. Hodson (7424300), David A. Barrett (50012), P. Nicholas Shaw (17220508), John A. Fuerst (17220505), Sarir Sarmad (17166775)   +7 more
core   +11 more sources

Imaging N-Acyl Homoserine Lactone Quorum Sensing In Vivo

, 2010
In order to study N-acyl homoserine lactone (AHL)-based quorum sensing in vivo, we present a protocol using an Escherichia coli strain equipped with a luxR-based monitor system, which in the presence of exogenous AHL molecules expresses a green fluorescent protein (GFP).
Hultqvist, Louise Dahl, Alhede, Maria, Jakobsen, Tim Holm, Givskov, Michael, Bjarnsholt, Thomas   +4 more
core   +7 more sources

Acylated homoserine lactones in the environment: chameleons of bioactivity [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2007
Over the last 15 years, it has become increasingly apparent that a single class of compounds, the acylated homoserine lactones (AHLs), elicit effects on many levels of biological and ecological organization. Despite the fact that the distribution of AHL production in the prokaryotic phylogenetic tree is restricted to a small set of genera ...
Manefield, Mike, Whiteley, Andrew S.
openaire   +3 more sources

Are There Acyl-Homoserine Lactones within Mammalian Intestines? [PDF]

Journal of Bacteriology, 2013
ABSTRACTManyProteobacteriaare capable of quorum sensing usingN-acyl-homoserine lactone (acyl-HSL) signaling molecules that are synthesized by LuxI or LuxM homologs and detected by transcription factors of the LuxR family. Most quorum-sensing species have at least one LuxR and one LuxI homolog.
Matthew C, Swearingen, Anice, Sabag-Daigle, Brian M M, Ahmer   +2 more
openaire   +2 more sources

Detection of acyl-homoserine lactones by Escherichia and Salmonella [PDF]

Current Opinion in Microbiology, 2011
Escherichia and Salmonella do not synthesize quorum-sensing signaling molecules of the N-acyl-l-homoserine lactone (AHL) type but they can detect AHLs produced by other species of bacteria. AHLs are present in the bovine rumen but not in the remainder of the gastrointestinal tract. Enterohemorrhagic E.
Jitesh A, Soares, Brian M M, Ahmer
openaire   +2 more sources

N-Acyl Homoserine Lactone Analog Modulators of the Pseudomonas aeruginosa Rhll Quorum Sensing Signal Synthase. [PDF]

ACS Chem Biol, 2019
Virulence in the Gram-negative pathogen Pseudomonas aeruginosa relies in part on the efficient functioning of two LuxI/R dependent quorum sensing (QS) cascades, namely, the LasI/R and RhlI/R systems that generate and respond to N-(3-oxo)-dodecanoyl-l ...
Shin D, Gorgulla C, Boursier ME, Rexrode N, Brown EC, Arthanari H, Blackwell HE, Nagarajan R.   +7 more
europepmc   +2 more sources

Acyl-Homoserine Lactone Quorum Sensing in the Roseobacter Clade [PDF]

International Journal of Molecular Sciences, 2014
Members of the Roseobacter clade are ecologically important and numerically abundant in coastal environments and can associate with marine invertebrates and nutrient-rich marine snow or organic particles, on which quorum sensing (QS) may play an important role.
Zan, Jindong, Liu, Yue, Fuqua, Clay, Hill, Russell T.   +3 more
openaire   +2 more sources

A Comparative Analysis of Acyl‐Homoserine Lactone Synthase Assays [PDF]

ChemBioChem, 2015
AbstractQuorum sensing is cell‐to‐cell communication that allows bacteria to coordinate attacks on their hosts by inducing virulent gene expression, biofilm production, and other cellular functions, including antibiotic resistance. AHL synthase enzymes synthesize N‐acyl‐l‐homoserine lactones, commonly referred to as autoinducers, to facilitate quorum ...
Daniel, Shin, Nicole D, Frane, Ryan M, Brecht, Jesse, Keeler, Rajesh, Nagarajan   +4 more
openaire   +2 more sources

Acyl Homoserine Lactones Induce Early Response in the Airway [PDF]

The Anatomical Record, 2009
AbstractAcyl homoserine lactones (AHLs) are intercellular signaling molecules used in quorum sensing by Gram‐negative bacteria. We studied the early effects on the rat airway of in vivo intratracheal administration of AHLs (i.e., P. aeruginosa and B. cepacia) to test the hypothesis that AHLs also act on the airway cells, modifying secretory mechanisms ...
SBARBATI, Andrea, Tizzano M., MERIGO, Flavia, BENATI, Donatella, NICOLATO, Elena, BOSCHI, Federico, CECCHINI, Maria Paola, SCAMBI, Ilaria, OSCULATI, Francesco   +8 more
openaire   +3 more sources