Results 11 to 20 of about 89,834 (290)
Mycobacterial acyl carrier protein suppresses TFEB activation and upregulates miR-155 to inhibit host defense [PDF]
Frontiers in Immunology, 2022 Mycobacterial acyl carrier protein (AcpM; Rv2244), a key protein involved in Mycobacterium tuberculosis (Mtb) mycolic acid production, has been shown to suppress host cell death during mycobacterial infection.
Seungwha Paik +21 more
doaj +2 more sources
Interfacial Enzymes Enable Gram-Positive Microbes to Eat Fatty Acids
Membranes, 2023 Exogenous fatty acid (eFA) activation and utilization play key roles in bacterial physiology and confer growth advantages by bypassing the need to make fatty acids for lipid synthesis.
Christopher D. Radka
doaj +1 more source
Frontiers in Microbiology, 2022 The fatty acid synthase type II (FAS-II) multienzyme system is the main target of drugs to inhibit mycolic acid synthesis in mycobacterium. Meromycolate extension acyl carrier protein (AcpM) serves as the carrier of fatty acyl chain shuttling among the ...
Mengmiao Li +7 more
doaj +1 more source
Acyl Carrier Protein in Mycoplasmas [PDF]
Journal of Bacteriology, 1973 Acyl carrier protein (ACP) activity was determined by the malonyl-coenzyme A–CO 2 exchange reaction. It was highest in Acholeplasma laidlawii , lower in A. granularum , and lowest in A. axanthum . The sterol-requiring Mycoplasma
S, Rottem, O, Muhsam-Peled, S, Razin
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Acylation of the Type 3 Secretion System Translocon Using a Dedicated Acyl Carrier Protein. [PDF]
PLoS Genetics, 2017 Bacterial pathogens often deliver effectors into host cells using type 3 secretion systems (T3SS), the extremity of which forms a translocon that perforates the host plasma membrane.
Julie P Viala +10 more
doaj +1 more source
Involvement of Arabidopsis Acyl Carrier Protein 1 in PAMP-Triggered Immunity
Molecular Plant-Microbe Interactions, 2022 Plant fatty acids (FAs) and lipids are essential in storing energy and act as structural components for cell membranes and signaling molecules for plant growth and stress responses.
Zhenzhen Zhao +6 more
doaj +1 more source
Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor [PDF]
, 2010 Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism.
Alam, Mohammad T. +6 more
core +13 more sources
F1000Research, 2022 Background: FabB (3-oxoacyl-[acyl-carrier-protein] synthase 1) is part of the fatty acid synthesis II pathway found in bacteria and a potential target for antibiotics.
Vladyslav Yadrykhins'ky +2 more
doaj +1 more source
Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]
Journal of the American Chemical Society, 2016 An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee +5 more
openaire +4 more sources
Evolution of acyl-substrate recognition by a family of acyl-homoserine lactone synthases. [PDF]
PLoS ONE, 2014 Members of the LuxI protein family catalyze synthesis of acyl-homoserine lactone (acyl-HSL) quorum sensing signals from S-adenosyl-L-methionine and an acyl thioester.
Quin H Christensen +4 more
doaj +1 more source