Results 21 to 30 of about 89,834 (290)
Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency
eLife, 2023 Malonyl-CoA-acyl carrier protein transacylase (MCAT) is an enzyme involved in mitochondrial fatty acid synthesis (mtFAS) and catalyzes the transfer of the malonyl moiety of malonyl-CoA to the mitochondrial acyl carrier protein (ACP).
Bryn D Webb +12 more
doaj +1 more source
Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases [PDF]
, 2009 Background - There is an urgent need for the discovery and development of new drugs against Mycobacterium tuberculosis, the causative agent of tuberculosis, especially due to the recent emergence of multi-drug and extensively-drug resistant strains ...
Alistair K. Brown +5 more
core +13 more sources
Dual Role of ACBD6 in the Acylation Remodeling of Lipids and Proteins
Biomolecules, 2022 The transfer of acyl chains to proteins and lipids from acyl-CoA donor molecules is achieved by the actions of diverse enzymes and proteins, including the acyl-CoA binding domain-containing protein ACBD6.
Eric Soupene, Frans A. Kuypers
doaj +1 more source
Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
, 2020 Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
core +2 more sources
Frontiers in Microbiology, 2022 The phospholipid acyl chains of Enterococcus faecalis can be derived either by de novo synthesis or by incorporation of exogenous fatty acids through the fatty acid kinase complex (Fak)-phosphate acyltransferase (PlsX) pathway.
Qi Zou +4 more
doaj +1 more source
NMR Studies of Escherichia Coli Acyl Carrier Protein: Dynamic and Structural Differences of the Apo- and Holo-forms [PDF]
, 2006 Two indicators of conformational variability of Escherichia coli acyl carrier protein (ACP) have been investigated, namely backbone dynamics and chemical shift variations of ACP.
Eletr, Ziad +2 more
core +2 more sources
Identifying Novel Inhibitors of RpFabG in Typhus-inducing Rickettsia prowazekii [PDF]
, 2019 Epidemic typhus is a rickettsial disease that is contracted via ticks and lice found on the flying squirrel. The disease is caused by Rickettsia prowazekii, an intracellular, gram-negative coccobacillus.
Panatpur, Aparna
core +1 more source
Transcriptome analysis of Listeria monocytogenes exposed to biocide stress reveals a multi-system response involving cell wall synthesis, sugar uptake, and motility [PDF]
, 2014 peer-reviewedListeria monocytogenes is a virulent food-borne pathogen most often associated with the consumption of “ready-to-eat” foods. The organism is a common contaminant of food processing plants where it may persist for extended periods of time.
Aidan eCasey +6 more
core +4 more sources
Biomolecules, 2021 The SLC25A20 transporter, also known as carnitine acyl-carnitine carrier (CAC), catalyzes the transport of short, medium and long carbon chain acyl-carnitines across the mitochondrial inner membrane in exchange for carnitine.
Annamaria Tonazzi +4 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2001 The acyl carrier protein NodF is required for the synthesis of unusual polyunsaturated fatty acids that confer specificity to lipochitin oligosaccharide nodulation (Nod) factors of Rhizobium leguminosarum. In this study, homogeneous NodF protein was used
Isabel M. López-Lara, Otto Geiger
doaj +1 more source