Results 21 to 30 of about 89,283 (289)

Involvement of Arabidopsis Acyl Carrier Protein 1 in PAMP-Triggered Immunity

Molecular Plant-Microbe Interactions, 2022
Plant fatty acids (FAs) and lipids are essential in storing energy and act as structural components for cell membranes and signaling molecules for plant growth and stress responses.
Zhenzhen Zhao, Jiangbo Fan, Piao Yang, Zonghua Wang, Stephen Obol Opiyo, David Mackey, Ye Xia   +6 more
doaj   +1 more source

Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics [version 2; peer review: 2 approved]

F1000Research, 2022
Background: FabB (3-oxoacyl-[acyl-carrier-protein] synthase 1) is part of the fatty acid synthesis II pathway found in bacteria and a potential target for antibiotics.
Vladyslav Yadrykhins'ky, Ruth Brenk, Charis Georgiou   +2 more
doaj   +1 more source

Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor [PDF]

, 2010
Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism.
Alam, Mohammad T., Breitling, Rainer, HASH(0x55aa09327868), Hodgson, D. A., Merlo, Maria E., Takano, Eriko, Wellington, E. M. H.   +6 more
core   +12 more sources

Evolution of acyl-substrate recognition by a family of acyl-homoserine lactone synthases. [PDF]

PLoS ONE, 2014
Members of the LuxI protein family catalyze synthesis of acyl-homoserine lactone (acyl-HSL) quorum sensing signals from S-adenosyl-L-methionine and an acyl thioester.
Quin H Christensen, Ryan M Brecht, Dastagiri Dudekula, E Peter Greenberg, Rajesh Nagarajan   +4 more
doaj   +1 more source

Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency

eLife, 2023
Malonyl-CoA-acyl carrier protein transacylase (MCAT) is an enzyme involved in mitochondrial fatty acid synthesis (mtFAS) and catalyzes the transfer of the malonyl moiety of malonyl-CoA to the mitochondrial acyl carrier protein (ACP).
Bryn D Webb, Sara M Nowinski, Ashley Solmonson, Jaya Ganesh, Richard J Rodenburg, Joao Leandro, Anthony Evans, Hieu S Vu, Thomas P Naidich, Bruce D Gelb, Ralph J DeBerardinis, Jared Rutter, Sander M Houten   +12 more
doaj   +1 more source

Direct structural analysis of a single acyl carrier protein domain in fatty acid synthase from the fungus Saccharomyces cerevisiae. [PDF]

Commun Biol
Samani EK, Chen AC, Lou JW, Dai DL, Keszei AFA, Tan G, Boone C, Grininger M, Mazhab-Jafari MT.   +8 more
europepmc   +3 more sources

A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic [PDF]

, 2011
Background Understanding how complex antibiotics are synthesised by their producer bacteria is essential for creation of new families of bioactive compounds. Thiomarinols, produced by marine bacteria belonging to the genus Pseudoalteromonas, are hybrids
Cox, Russell J., Crosby, John, Fukuda, Daisuke, Gurney, Rachel, Haines, Anthony S., Hothersall, Joanne, Murphy, Annabel C., Simpson, Thomas J., Song, Zhongshu, Stephens, Elton R., Thomas, Christopher M., Willis, Christine L.   +11 more
core   +13 more sources

Dual Role of ACBD6 in the Acylation Remodeling of Lipids and Proteins

Biomolecules, 2022
The transfer of acyl chains to proteins and lipids from acyl-CoA donor molecules is achieved by the actions of diverse enzymes and proteins, including the acyl-CoA binding domain-containing protein ACBD6.
Eric Soupene, Frans A. Kuypers
doaj   +1 more source

NMR Studies of Escherichia Coli Acyl Carrier Protein: Dynamic and Structural Differences of the Apo- and Holo-forms [PDF]

, 2006
Two indicators of conformational variability of Escherichia coli acyl carrier protein (ACP) have been investigated, namely backbone dynamics and chemical shift variations of ACP.
Eletr, Ziad, Kim, Yangmee, Kovriguine, Evgueni   +2 more
core   +2 more sources

The Enterococcus faecalis FabT Transcription Factor Regulates Fatty Acid Biosynthesis in Response to Exogeneous Fatty Acids

Frontiers in Microbiology, 2022
The phospholipid acyl chains of Enterococcus faecalis can be derived either by de novo synthesis or by incorporation of exogenous fatty acids through the fatty acid kinase complex (Fak)-phosphate acyltransferase (PlsX) pathway.
Qi Zou, Huijuan Dong, Lei Zhu, John E. Cronan, John E. Cronan   +4 more
doaj   +1 more source