Results 51 to 60 of about 10,947 (199)
Frontiers in Public Health, 2023 AimsGestational diabetes mellitus (GDM) stands as a prevalent obstetric complication bearing consequential health implications for both mother and child.
Hairong Luo, Zanlei Zhu
doaj +1 more source
JPGN Reports, EarlyView.Abstract Recurrent episodic abdominal pain and vomiting, with symptom‐free intervals between attacks, represent common and often challenging presentations in children, typically leading to extensive workups without a clear etiology, as standard diagnostic algorithms fail to include rare systemic conditions. We present the challenging diagnostic odyssey
Julio Nestor Busaniche +8 more
wiley +1 more source
Postnatal variations in blood free and acylcarnitines [PDF]
Journal of Clinical Laboratory Analysis, 2011 AbstractBackground: Alteration in concentrations of blood carnitine and its esters are diagnostic of a number of inherited metabolic disorders. Acylcarnitine (AC) profiles of newborns obtained from dried blood spots by tandem mass spectrometric analysis are being used for the diagnosis of these disorders.
Tanima, De +3 more
openaire +2 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background Variants in AFG3‐Like Matrix AAA Peptidase, Subunit 2 (AFG3L2) gene are associated with diverse clinical phenotypes. Here, we describe phenotypic findings of two unrelated children with de novo heterozygous variant and one family with inherited heterozygous variant in AFG3L2 gene.
Sangeetha Yoganathan +14 more
wiley +1 more source
Correlation between Acylcarnitine and Peripheral Neuropathy in Type 2 Diabetes Mellitus
Journal of Diabetes Research, 2022 Objective. In patients with type 2 diabetes mellitus (T2DM), it is unknown whether acylcarnitine changes in the patient’s plasma as diabetic peripheral neuropathy (DPN) occurs.
Zhenni An +5 more
doaj +1 more source
Movement Disorders, EarlyView.Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik +5 more
wiley +1 more source
Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach. [PDF]
PLoS ONE, 2018 Structural equation modeling (SEM) can help understanding complex functional relationships among obesity, non-alcoholic fatty liver disease (NAFLD), family history of obesity, targeted metabolomics and pro-inflammatory markers.
Maria Elena Romero-Ibarguengoitia +10 more
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Postnatal Changes in Neonatal Acylcarnitine Profile [PDF]
Pediatric Research, 2001 ++Electrospray-tandem mass spectrometry represents a powerful method for detection of inborn errors of fatty acid metabolism. In the present study, it was used to examine neonatal carnitine metabolism, which reflects fatty acid metabolism. In 70 healthy neonates, blood samples were taken from the umbilical cord and by heel-stick puncture in full-term ...
J, Meyburg +4 more
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Environmental Toxicology, EarlyView.ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley +1 more source
Metabolites, 2018 The plasma metabolome is associated with multiple phenotypes and diseases. However, a systematic study investigating clinical determinants that control the metabolome has not yet been conducted.
Mahmoud Al-Majdoub +6 more
doaj +1 more source