Results 91 to 100 of about 63,314 (347)

Induction of Cell Death by Combined Treatment with Photosensitizer‐Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study demonstrates that combination of phosphosensitizer‐conjugated chitosan nanoparticles and ferroptosis inducer RSL3 increases cell death in mesenchymal breast cancer cells. Data suggests that this is attributed to variations in ferroptosis‐related protein expression, lipid peroxydation and mitochondrial function.
Marek Feith, Saikat Das Sajib, Anne Grethe Myrann, Anders Høgset, Pablo Garrido, Alfredo Martinez, Erik Knutsen, Kirsten Sandvig, Tore Skotland, Gunhild Mari Mælandsmo, Tore‐Geir Iversen   +10 more
wiley   +1 more source

Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance Lysophospholipid acyltransferase (LPLAT) proteins are required for many essential biological activities involving the transfer of acyl chains.
D. Dovala, C. Rath, Qijun Hu, William S. Sawyer, S. Shia, R. Elling, M. Knapp, L. Metzger   +7 more
semanticscholar   +1 more source

Overexpression of diacylglycerol acyltransferase in Yarrowia lipolytica affects lipid body size, number and distribution.

FEMS Yeast Research, 2016
In the oleaginous yeast Yarrowia lipolytica, the diacylglycerol acyltransferases (DGATs) are major factors for triacylglycerol (TAG) synthesis. The Q4 strain, in which the four acyltransferases have been deleted, is unable to accumulate lipids and to ...
P. Gajdoš, Rodrigo Ledesma-Amaro, J. Nicaud, M. Čertík, Tristan Rossignol   +4 more
semanticscholar   +1 more source

A Grapevine Anthocyanin Acyltransferase, Transcriptionally Regulated by VvMYBA, Can Produce Most Acylated Anthocyanins Present in Grape Skins1

Plant Physiology, 2015
An anthocyanin acyltransferase with an unusual substrate flexibility is truncated in cv Pinot Noir, a grapevine cultivar lacking acylated red pigments.
A. Rinaldo, Erika Cavallini, Yong Jia, S. Moss, D. McDavid, L. C. Hooper, S. Robinson, G. B. Tornielli, S. Zenoni, C. Ford, P. Boss, A. R. Walker   +11 more
semanticscholar   +1 more source

Acylation of monolysocardiolipin in rat heart

Journal of Lipid Research, 1999
Cardiolipin is a major mitochondrial membrane glycerophospholipid in the mammalian heart. In this study, the ability of the isolated intact rat heart to remodel cardiolipin and the mitochondrial enzyme activities that reacylate monolysocardiolipin to ...
Brian J. Ma, William A. Taylor, Vernon W. Dolinsky, Grant M. Hatch   +3 more
doaj  

Could Duodenal Molecular Mechanisms be Involved in the Hypocholesterolemic Effect of Silicon Used as Functional Ingredient in Late‐Stage Type 2 Diabetes Mellitus?

Molecular Nutrition &Food Research, Volume 66, Issue 24, December 2022., 2022
Duodenal mucosa in early‐stage type 2 diabetes mellitus (ED), late‐stage type 2 diabetes mellitus injected with streptozotocin‐nicotinamide (STZ/NAD) (LD) and treated‐silicon LD (LD‐Si) groups. Silicon partially reversed LD group alterations: decreased absorptive area and acyl‐Coenzyme A:cholesterol acyltransferase 2 (ACAT2) levels, and increased ...
Marina Hernández‐Martín, Aránzazu Bocanegra, Rocío Redondo‐Castillejo, Adrián Macho‐González, Francisco J. Sánchez‐Muniz, Juana Benedí, Sara Bastida, Rosa A. García‐Fernández, Alba Garcimartín, M. Elvira López‐Oliva   +9 more
wiley   +1 more source

An involvement of phospholipase A/acyltransferase family proteins in peroxisome regulation and plasmalogen metabolism

FEBS Letters, 2017
The H‐Ras‐like suppressor (HRASLS) is a protein family consisting of five members in humans. Despite their discovery as tumor suppressors, we demonstrated that all these proteins are phospholipid‐metabolizing enzymes, such as phospholipase (PL) A1/A2 and
T. Uyama, K. Tsuboi, N. Ueda
semanticscholar   +1 more source

Mining the active proteome of Arabidopsis thaliana

Frontiers in Plant Science, 2011
Assigning functions to the >30.000 proteins encoded by the Arabidopsis genome is a challenging task of the Arabidopsis Functional Genomics Network.
Renier A. L. Van Der Hoorn, Tom eColby, Sabrina eNickel, Kerstin eRichau, Juergen eSchmidt, Markus eKaiser   +5 more
doaj   +1 more source

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Nature Communications, 2016
The biosynthesis of phospholipids and glycolipids are critical pathways for virtually all cell membranes. PatA is an essential membrane associated acyltransferase involved in the biosynthesis of mycobacterial phosphatidyl-myo-inositol mannosides (PIMs ...
D. Albesa-Jové, Zuzana Svetlíková, M. Tersa, E. Sancho-Vaello, A. Carreras-González, P. Bonnet, P. Arrasate, Ander Eguskiza, S. K. Angala, J. Cifuente, Jana Korduláková, M. Jackson, K. Mikušová, M. Guerin   +13 more
semanticscholar   +1 more source

Molecular species of phosphatidylcholine in abetalipoproteinemia: effect of lecithin:cholesterol acyltransferase and lysolecithin acyltransferase.

Journal of Lipid Research, 1989
In order to study the role of very low density lipoproteins (VLDL) and low density lipoproteins (LDL) in determining the molecular species composition of phosphatidylcholine (PC) and the specificity of lecithin:cholesterol acyltransferase (LCAT) in human plasma, we studied the PC species composition in plasma from abetalipoproteinemic (ABL) and control
R. E. Gregg, Papasani V. Subbaiah, John D. Bagdade, B. Banerji   +3 more
openaire   +4 more sources