Results 71 to 80 of about 58,529 (305)

Diacylglycerol acyltransferase genes in peanut.

, 2014
Diacylglycerol acyltransferase genes in peanut.
Mingna Chen (153303), Tong Wang (87696), Shanlin Yu (153337), Na Chen (153323), Ruibo Hu (182951), Mian Wang (153332), Xiaoyuan Chi (153312), Quanfu Wang (624485), Zhen Yang (107412), Xiaowen Zhang (83669), Lijuan Pan (153317)   +10 more
core   +1 more source

Membrane Topology of Hedgehog Acyltransferase [PDF]

Journal of Biological Chemistry, 2015
Hedgehog acyltransferase (Hhat) is a multipass transmembrane enzyme that mediates the covalent attachment of the 16-carbon fatty acid palmitate to the N-terminal cysteine of Sonic Hedgehog (Shh). Palmitoylation of Shh by Hhat is critical for short and long range signaling.
Armine, Matevossian, Marilyn D, Resh
openaire   +2 more sources

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Corneal Haze and Peripheral Corneal Arcus in a Young Patient: Lecithin-Cholesterol Acyltransferase Deficiency

, 2014
A 23-year-old female patient applied to our clinic with the complaints of color changes in both of her corneas. Ophthalmological examination revealed 20/20 vision in both eyes.
Çağdaş Cansız, Hüseyin Mayalı, Şaban Kılıç, Esin Fatma Başer, Mehmet Şirin Türkoğlu   +4 more
core   +1 more source

Catalytic properties of MGAT3, a putative triacylgycerol synthases⃞

Journal of Lipid Research, 2007
Acyl-coenzyme A:monoacylglycerol acyltransferase 3 (MGAT3) is a member of the MGAT family of enzymes that catalyze the synthesis of diacylglycerol (DAG) from monoacylglycerol (MAG), a committed step in dietary fat absorption.
Jingsong Cao, Long Cheng, Yuguang Shi
doaj   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Inhibition of lecithin cholesterol acyltransferase by phosphatidylcholine hydroperoxides

, 1999
To gain insight into the nature of the lecithin-cholesterol acyltransferase inhibitory factor(s), we separated and collected the oxidation products from oxidized lipoproteins after lipoxygenase treatment.
Moatti, Nicole, Thérond, Patrice, Legrand, Alain, Davit-Spraul, Anne, Leroy, Arnaud, Céline Rousset, Alain Legrand, Nicole Moatti, Anne Davit-Spraul, Arnaud Leroy, Rousset, Céline, Palmade-Rieunier, Françoise, Françoise Palmade-Rieunier, Patrice Thérond   +13 more
core   +1 more source

Role of plasma lecithin:cholesterol acyltransferase in the metabolism of high density lipoproteins

Journal of Lipid Research, 1966
The role of the plasma lecithin:cholesterol acyltransferase reaction in the esterification of the cholesterol of human and baboon plasma high density lipoproteins has been studied.Human plasma was incubated in vitro, and the initial rate of cholesterol ...
J.A. Glomset, E.T. Janssen, R. Kennedy, J. Dobbins   +3 more
doaj   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Acyl-coenzyme A:cholesterol acyltransferases [PDF]

American Journal of Physiology-Endocrinology and Metabolism, 2009
The enzymes acyl-coenzyme A (CoA):cholesterol acyltransferases (ACATs) are membrane-bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form cholesteryl esters. In mammals, two isoenzymes, ACAT1 and ACAT2, encoded by two different genes, exist.
Ta-Yuan, Chang, Bo-Liang, Li, Catherine C Y, Chang, Yasuomi, Urano   +3 more
openaire   +2 more sources