Results 61 to 70 of about 58,776 (313)

Molecular studies on plant glycerol-s-phosphate acyltransferases [PDF]

open access: yes, 2000
The main objective of this research is to advance our understanding of the biochemical properties and the structure-function relationships of the chloroplast glycerol-3-phosphate acyltransferases in plants.
Kroon, Johannes Theodorus Maria
core  

Effect of Early Enteral Feeding on Apolipoprotein AI Levels and High-Density Lipoprotein Heterogeneity in Preterm Infants [PDF]

open access: yes, 2001
Background/Aim: We have previously shown that infants receiving total parenteral nutrition have low apolipoprotein Al levels which are associated with high-density lipoprotein (HDL) class distributions as in lecithin:cholesterol acyltransferase ...
Berthold Koletzkob   +5 more
core   +1 more source

A novel pathway for lipid biosynthesis: the direct acylation of glycerol

open access: yesJournal of Lipid Research, 2001
The acylation of glycerol-3-phosphate by acyl-CoA is regarded as the first committed step for the synthesis of the lipoidal moiety in glycerolipids. The direct acylation of glycerol in mammalian tissues has not been demonstrated.
Douglas P. Lee   +6 more
doaj   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

Molecular and structural studies on proteins involved in lipid biosynthesis in plants and bacteria [PDF]

open access: yes, 2002
Fatty acid synthesis in plants and most bacteria is catalysed by a type II, dissociable fatty acid synthetase, critically involving the participation of acyl-carrier protein (ACP) during synthesis and elongation reactions. This provides the substrate for
Simon, Josiah William
core  

Microsomal glycerolphosphate acyltransferase inactivation by fatty acids [PDF]

open access: yes, 1990
Glycerolphosphate acyltransferase activity in microsomes from rat adipose tissue is shown to decrease with time upon incubation with adipose tissue cytosolic fraction.
M. A. Rodriguez, V. Durocher, M. Miller
core   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu   +5 more
wiley   +1 more source

Biotransormations with plant coenzyme A-dependent acyltransferases [PDF]

open access: yes, 2008
The acylation of plant natural products is widely observed in nature and this modification often confers novel bioactivities. In nature, each of these acylations is selectively catalysed by a coenzyme A-dependent acyltransferase and biotransformations ...
Cunningham, Oliver David
core  

Studies of rat adipose-tissue microsomal glycerol phosphate acyltransferase [PDF]

open access: yes, 1984
Incubation of rat adipose-tissue microsomal fractions with iodoacetate caused an inactivation of glycerol phosphate acyltransferase that could be prevented by the presence of palmitoyl-CoA.
Nimmo, G.A., Nimmo, H.G.
core   +1 more source

The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases

open access: yesMolecules, 2011
Polyketides are a diverse class of medically important natural products whose biosynthesis is catalysed by polyketide synthases (PKSs), in a fashion highly analogous to fatty acid biosynthesis.
David H. Kwan, Frank Schulz
doaj   +1 more source

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