Results 131 to 140 of about 101,485 (290)

Fatty acyl recognition and transfer by an integral membrane S-acyltransferase

open access: yesScience, 2018
M. Rana   +5 more
semanticscholar   +1 more source

Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria[S]

open access: yesJournal of Lipid Research, 2011
The enzyme 1-acylglycerol-3-phosphate-O-acyltransferase (AGPAT) converts lysophosphatidic acid (LPA) to phosphatidic acid (PA). In this study, we show enzymatic properties, tissue distribution, and subcellular localization of human AGPAT3 and AGPAT5.
Sneha S. Prasad   +2 more
doaj  

Alkyne lipids as substrates for click chemistry-based in vitro enzymatic assays

open access: yesJournal of Lipid Research, 2013
Click chemistry is evolving as a powerful tool in biological applications because it allows the sensitive and specific detection of compounds with alkyne or azido groups.
Anne Gaebler   +5 more
doaj  

Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2−/− lipodystrophic mice independent of hepatocyte leptin receptors[S]

open access: yesJournal of Lipid Research, 2014
Leptin is essential for energy homeostasis and regulation of food intake. Patients with congenital generalized lipodystrophy (CGL) due to mutations in 1-acylglycerol-3-phosphate-O-acyltransferase 2 (AGPAT2) and the CGL murine model (Agpat2−/− mice) both ...
Víctor A. Cortés   +5 more
doaj  

GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis[S]

open access: yesJournal of Lipid Research, 2010
Acyl-CoA:glycerol-3-phosphate acyltransferase (GPAT) catalyzes the first step during de novo synthesis of glycerolipids. Mammals have at least four GPAT isoforms. Here we report the further characterization of the two recently identified microsomal GPAT3
Dandan Shan   +7 more
doaj  

Selective Transfer of Cyclopropane Acids by Acyl Coenzyme A:Phospholipid Acyltransferases

open access: hybrid, 1969
Harumi Okuyama   +3 more
openalex   +1 more source

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