Results 131 to 140 of about 63,314 (347)

Involvement of a putative acyltransferase gene in sporangium formation in Actinoplanes missouriensis

Microbiology Spectrum
The actinomycete Actinoplanes missouriensis forms branched substrate mycelia during vegetative growth and produces terminal sporangia, each of which contains a few hundred spherical flagellated spores, from the substrate mycelia through short ...
Shixuan Hu, Satoshi Maeda, Takeaki Tezuka, Yasuo Ohnishi   +3 more
doaj   +1 more source

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

ChemistryEurope, EarlyView.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

Silencing AT3 gene reduces the expression of pAmt, BCAT, Kas, and Acl genes involved in capsaicinoid biosynthesis in chili pepper fruits

Biologia Plantarum, 2015
The effects of AT3-gene silencing on the expression of genes involved in capsaicinoid biosynthesis was investigated in chili pepper (Capsicum annuum L.) cv. Tampiqueño 74 fruits.
M. L. Arce-Rodríguez, N. Ochoa-Alejo
doaj   +1 more source

Penicillin Acyltransferase in Penicillium chrysogenum [PDF]

, 1967
David L. Pruess, Marvin J. Johnson
openalex   +1 more source

Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein

Journal of Biological Chemistry, 2014
Background: Hedgehog acyltransferase (HHAT) palmitoylates hedgehog proteins and is a potential target in cancer. Results: HHAT has ten transmembrane domains, two reentrant loops, and four palmitoylation sites. Conclusion: HHAT topology is determined, and
A. Konitsiotis, B. Jovanović, Paulina Ciepla, M. Spitaler, Thomas Lanyon-Hogg, Edward W. Tate, A. Magee   +6 more
semanticscholar   +1 more source

Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe, Timothy Nicholas, Gianluca Nucci, Cynthia J Musante, Brian Corrigan   +4 more
wiley   +1 more source

Purification and properties of acyltransferases from Pseudomonas aeruginosa [PDF]

, 1964
Michael T. Kelly, HL KORNBERG
openalex   +1 more source

Computational Study of the Fries Rearrangement Catalyzed by Acyltransferase from Pseudomonas protegens

ChemistryOpen
The acyltransferase from Pseudomonas protegens (PpATase) catalyzes in nature the reversible transformation of monoacetylphloroglucinol to diacetylphloroglucinol and phloroglucinol.
Xiang Sheng, Wolfgang Kroutil, Fahmi Himo   +2 more
doaj   +1 more source

Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops

Food Frontiers, EarlyView.
ABSTRACT Due to rapid global population growth and the resulting significant increase in food demand, the world is facing an epidemic of malnutrition. Although yield improvement remains one of the main targets of breeding programs, much attention is being paid to the nutritional aspects of crops, including nutrients and bioactive compounds that are ...
Maria Dellino, Claudio de Giovanni, Monica Marilena Miazzi, Cinzia Montemurro, Domenica Nigro   +4 more
wiley   +1 more source

Biosynthesis of Penicillins. I. Isolation of a 6-Aminopenicillanic Acid Acyltransferase from Penicillium chrysogenum. [PDF]

, 1968
Sten Gatenbeck, Urban Brunsberg, Sakari Närvänen, Robert McCrindle, R. D. H. Murray   +4 more
openalex   +1 more source