Results 191 to 200 of about 58,776 (313)

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Phospholipid Networks as Metabolic Hubs and Signaling Integrators in Plant Development and Stress Adaptation. [PDF]

Plants (Basel)
Chang P, Ju M, Cao H, Duan Y, Tian Q, Mu C, Li G, Feng X, Hou W, Zhang H, Miao H.   +10 more
europepmc   +1 more source

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga, Silvia Frigo, Alessandro Cherubini, Eniada Rrapaj, Luca Valenti   +4 more
wiley   +1 more source

APOC3 Promotes DGAT2-Dependent Triglyceride Accumulation in Hepatocytes During Early Metabolic Dysfunction. [PDF]

Biomolecules
Nguyen TN, Kim HJ, Shim HM, Kang J, Ha EY, Cho H, Park JH.   +6 more
europepmc   +1 more source

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal, Caden M. Fritson, Alexandra Seas, Heidi Vieira, Surinder K. Batra   +4 more
wiley   +1 more source

O-acyltransferase genes involved in the production of volatile sex pheromones in <i><i>Caenorhabditis elegans</i></i>. [PDF]

Proc Natl Acad Sci U S A
Wan X, Cohen SM, Yu Y, Hoan Le H, Park H, Groaz A, Moreno R, Tan M, Schneider J, Gronquist MR, Shinya R, Schroeder FC, Sternberg PW.   +12 more
europepmc   +1 more source

The Postprandial Chronobiome in Interorgan Glucose Homeostasis

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
The postprandial chronobiome framework proposes that meal‐timed oscillations in microbial communities and metabolites may interact with host tissue clocks to shape glucose handling. The liver is the best‐supported temporal interpreter, while phase‐aware human studies are needed to establish causal interorgan effects.
Josko Bozic, Roko Santic, Marko Kumric
wiley   +1 more source

Quantitative Assessment of Visual Function in Japanese Patients With Lecithin-Cholesterol Acyltransferase Gene Abnormalities: A Case-Control Study. [PDF]

Cureus
Ono T, Iwasaki T, Sakisaka T, Mori Y, Nejima R, Miyata K.   +5 more
europepmc   +1 more source

Plasma Membrane Remodeling During Microglial Activation: A Hypothesis Linking Microglial Shape and Lipid Droplet Formation

Glia, Volume 74, Issue 8, August 2026.
Microglial morphology changes in response to damage by Aβ and aging result in significant reductions in cell surface area. Transcriptomic analyses suggest that fatty acid synthesis and triacylglycerol formation drive redistribution of surface membrane into intracellular lipid droplets.
G. William Rebeck, Giorgi Shautidze, Jordy Sepulveda, Gracie S. Healey, Priyanka S. Narayan   +4 more
wiley   +1 more source

Genome-wide analysis of DGAT gene family in Coix lacryma jobi L. and functional characterization in yeast H1246. [PDF]

BMC Plant Biol
Feng T, Gao J, Li Y, Yang L, Zhang X, Dong J, Liang Z.   +6 more
europepmc   +1 more source