Results 191 to 200 of about 58,529 (305)

Phospholipid Networks as Metabolic Hubs and Signaling Integrators in Plant Development and Stress Adaptation. [PDF]

Plants (Basel)
Chang P, Ju M, Cao H, Duan Y, Tian Q, Mu C, Li G, Feng X, Hou W, Zhang H, Miao H.   +10 more
europepmc   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

APOC3 Promotes DGAT2-Dependent Triglyceride Accumulation in Hepatocytes During Early Metabolic Dysfunction. [PDF]

Biomolecules
Nguyen TN, Kim HJ, Shim HM, Kang J, Ha EY, Cho H, Park JH.   +6 more
europepmc   +1 more source

The BAHD Acyltransferase Gene Family: Evolutionary Dynamics, Biochemical Mechanisms, and Roles in Plant Stress Adaptation. [PDF]

Plant Biotechnol J
BAHD acyltransferases drive metabolic diversification in plants by coupling conserved catalytic scaffolds with regulatory flexibility, enabling stress adaptation and ecological specialisation. ABSTRACT BAHD acyltransferases constitute one of the most versatile enzyme superfamilies in plants, catalysing the acylation of alcohols, amines, polyamines, and
Zafar MM, Fei Q, Razzaq A, Siddiqua A, Naveed A, Khan MN, Saleem H, Jiang X.   +7 more
europepmc   +2 more sources

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, Volume 36, Issue 4, July 2026.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Functional Prediction of <i>AT5G35460</i> Reveals Its Regulatory Role in Reproductive Development and Lipid Remodeling in <i>Arabidopsis thaliana</i>. [PDF]

Membranes (Basel)
Shabbir MA, Mubeen M, Umer M, Abbas A, Ali A, Qureshi SA, Rao MJ, Iftikhar Y, Alyami EM, Ahmed AE.   +9 more
europepmc   +1 more source

Context‐Dependent Effects of Apolipoprotein A2 on Lipid Metabolism and Atherogenesis

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Proposed model of the pro‐atherogenic role of APOA2 in dyslipidemia. Under conditions of dyslipidemia (ldlr−/− and apoe−/− mice), APOA2 promotes a reduction in VLDL through its conversion to LDL via an LDLR‐independent pathway. LDL is then deposited to the aorta and aortic root. In the ldlr−/− mice, the presence of APOE may mitigate the rate of VLDL to
Evangelia Zvintzou, Ioana Madalina Fenyo, Radu Ionita, Georgia Kakafoni, Madalina Dumitrescu, Maria Alemi, Bianca Sanziana Daraban, Konstantinos Marinos, Anca Violeta Gafencu, Kyriakos E. Kypreos   +9 more
wiley   +1 more source

Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Brice Beauvais, Rajendra Rohokale, Sevin Mamputu, Ion Lupu, Zhongwu Guo, Sébastien Balieu   +5 more
wiley   +1 more source

O-acyltransferase genes involved in the production of volatile sex pheromones in <i><i>Caenorhabditis elegans</i></i>. [PDF]

Proc Natl Acad Sci U S A
Wan X, Cohen SM, Yu Y, Hoan Le H, Park H, Groaz A, Moreno R, Tan M, Schneider J, Gronquist MR, Shinya R, Schroeder FC, Sternberg PW.   +12 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source