Results 221 to 230 of about 58,529 (305)

Evidence‐Based Clinical Practice Guidelines for Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) 2026

open access: yesHepatology Research, Volume 56, Issue 6, Page 887-902, June 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, with an increasing number of patients progressing to cirrhosis and hepatocellular carcinoma (HCC). Early identification of individuals at high risk for advanced fibrosis is essential for preventing liver‐related ...
Norio Akuta   +44 more
wiley   +1 more source

FTO‐Catalysed Demethylation of LUR1 mRNA Suppresses Macrophage Lipid Accumulation and Aortic Atherosclerosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Lipid deposition and foam cell formation drive atherogenesis. Lipid uptake regulator 1 (LUR1) and N6‐methyladenosine (m6A) modification play key roles in systemic lipid homeostasis. Bioinformatic analyses revealed a negative correlation between fat mass and obesity‐associated protein (FTO) and LUR1 expression and abundant m6A sites within the ...
Xiang‐Yang Tang   +5 more
wiley   +1 more source

Inhibitory Effects of Litchi Extract on Sebum Secretion and Its Mechanism: Evidence From a Mouse Model and Sebaceous Gland Cell Transcriptomics

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Objective Acne vulgaris is one of the most common chronic inflammatory dermatological disorders, affecting 85%–100% of adolescents and persisting into adulthood for a significant portion of the population. Litchi chinensis, a subtropical fruit originating from Southern China and famously associated with the Guangzhou region, is commercially ...
Qinqian Tao   +4 more
wiley   +1 more source

Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Polymorphisms of group VIA calcium‐independent phospholipase A2 (iPLA2β or PLA2G6) are associated with Type‐2 diabetes, blood lipids and inflammation. Global deficiency in iPLA2β‐null mice elicited protection against hepatic steatosis but not hepatic inflammation after high‐fat diet (HFD) feeding.
Gang Li   +4 more
wiley   +1 more source

Biocatalytic Regioselective C-Formylation of Resorcinol Derivatives. [PDF]

open access: yesAngew Chem Int Ed Engl
Gal L   +6 more
europepmc   +1 more source

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