Summary Metabolic engineering of vegetative tissues for lipid production holds transformative potential for sustainable biofuels, yet achieving sufficient yields remains challenging. Here, we present a strategy to enhance fatty acid synthesis by redirecting cytosolic phosphoenolpyruvate (PEP) into plastids through overexpression of the plastidial ...
Jiang Wang +6 more
wiley +1 more source
BnaC03.SEIPIN1 improves seed oil content by increasing the number of lipid droplets in Brassica napus. [PDF]
Li Y +8 more
europepmc +1 more source
Ornithine lipids and other acyloxyacyl amino lipids: the coming-of-age story of a group of non-canonical membrane lipids. [PDF]
Moyano-Palazuelo D +2 more
europepmc +1 more source
Chloroplast glycerolipid metabolism during maintenance and under stress
SUMMARY Chloroplasts are the defining organelles in green plant tissues, converting light into chemical energy with the help of an intricate and extensive membrane system, the thylakoids. In the process, they release oxygen and assimilate carbon and other elements into molecules that constitute a plant cell's building blocks.
Yosia Mugume +2 more
wiley +1 more source
Molecular basis of fatty acid composition diversity in different avocado cultivars. [PDF]
Chen M +9 more
europepmc +1 more source
This study investigates the role of the vision gene RGR using novel dual knockout zebrafish models. The loss of rgra and rgrb results in zebrafish larvae having reduced visual function and altered retinoid profiles under light but not dark conditions. The OKR phenotype is enhanced under higher light intensities.
Grace Ruddin +13 more
wiley +1 more source
Comparative histomorphometric and transcriptomic analysis reveals potential genetic determinants of pelage variation between hairy and coarse-woolly sheep. [PDF]
Liang Q +11 more
europepmc +1 more source
Bats can sustain powered flight, but their reliance on fatty acid oxidation may limit long‐distance migration compared to birds. Using untargeted metabolomics, we analyzed blood metabolites of Nathusius' pipistrelle under controlled flight and migratory field conditions to identify fuel use.
Alesia Walker +7 more
wiley +1 more source
Opposite diacylglycerol enantiomeric specificities of Arabidopsis DGAT1 and DGAT2 reveal distinct roles in TAG synthesis. [PDF]
Jaison CA +5 more
europepmc +1 more source
Engineering an Acyl‐CoA Ligase With Enhanced Activity Toward Synthetic CoA Alternatives
Engineering an acyl‐CoA ligase shifts thiol specificity toward inexpensive synthetic thiols such as N‐acetylcysteamine (SNAC), enabling enzymatic generation of acyl‐SNAC starter units that support polyketide biosynthesis. Fatty acyl‐coenzyme A (CoA) thioesters are indispensable intermediates in primary metabolism and essential building blocks for ...
Jared R. Cossin +2 more
wiley +1 more source

