Results 151 to 160 of about 67,878 (248)

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

open access: yesThe FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh   +7 more
wiley   +1 more source

Description of the rate-limiting hydrogen tunneling mechanism for plant 9- and 13-lipoxygenases. [PDF]

open access: yesProtein Sci
Kockler A   +7 more
europepmc   +1 more source

Short‐term survival of mallards following external transmitter attachment

open access: yesIbis, EarlyView.
Capturing birds for external transmitter attachment allows researchers to collect abundant movement and behavioural data across spatial and temporal gradients but can expose birds to additional stress due to prolonged handling, sometimes leading to mortality.
Cassidy L. Waldrep   +13 more
wiley   +1 more source

Trk1 potassium transport is crucial for effective <i>Candidozyma auris</i> skin colonization. [PDF]

open access: yesProc Natl Acad Sci U S A
Glawe AJ   +7 more
europepmc   +1 more source

Endemic but not eroded: Genomic distinctiveness and conservation genomics of the British swallowtail butterfly (Papilio machaon britannicus)

open access: yesInsect Conservation and Diversity, EarlyView.
Through whole‐genome sequencing of P. machaon populations across Europe, we demonstrate that P. m. britannicus forms a genetically distinct and isolated lineage. Demographic modelling revealed weak historical gene flow from the continent. Although P. m.
Benoit Nabholz   +6 more
wiley   +1 more source

Physical Implausibility of Carbohydrate Ligands in Results of Deep Learning-Based Cofolding Methods. [PDF]

open access: yesJ Chem Inf Model
Luthfi M   +4 more
europepmc   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh   +5 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du   +4 more
wiley   +1 more source

Sequence and structural alignments reveal insights into ANKLE2 evolution and function. [PDF]

open access: yesProtein Sci
Fishburn AT   +8 more
europepmc   +1 more source

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