Results 161 to 170 of about 75,759 (281)

Exploring epigenome-proteome interactions underlying post-surgical progression of non-functioning pituitary adenomas using hypernetwork modelling. [PDF]

J Transl Med
Suman M, Hallén T, Garner T, Thorsell A, Stevens A, Köster L, Carén H, Ragnarsson O, Skoglund T, Johannsson G.   +9 more
europepmc   +1 more source

Connecting Seed Lists of Mammalian Proteins Using Steiner Trees

, 2008
Multivariate experiments and genomics studies applied to mammalian cells often produce lists of genes or proteins altered under treatment/disease vs. control/normal conditions. Such lists can be identified in known protein-protein interaction networks to
Avi Ma'ayan, Amelia G. White
core   +1 more source

Does nature shape risk preferences? Evidence from Chile, Norway, and Tanzania

Economic Inquiry, Volume 63, Issue 2, Page 568-590, April 2025.
Abstract Does exposure to a more risky environment affect risk preferences? Going beyond single‐case study evidence, we report results from five surveys conducted in three countries and link this with administrative data to study whether a link between exposure and preferences is detectable and widespread. We find no evidence for endogenous preferences
Florian Diekert, Robbert‐Jan Schaap
wiley   +1 more source

Molecular de-extinction looks to the past to find the molecules of the future. [PDF]

Proc Natl Acad Sci U S A
Adam D.
europepmc   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Lipids challenge ligands to control receptors. [PDF]

Elife
Wollman AJM.
europepmc   +1 more source

Disruption of iron metabolism resulting from Dmt1/Slc11a2 deficiency compromises Notch protein degradation and transcriptional activation

The FEBS Journal, EarlyView.
Divalent metal transporter 1 (Dmt1) maintains iron homeostasis and lysosomal proteostasis required for physiological Notch receptor–ligand signaling. Dmt1 loss lowers iron storage capacity (ferritin), increasing intracellular Fe2+, driving ROS and lipid peroxidation, and leading to lysosomal/mitochondrial dysfunction.
Rui Zhang, Somaieh Ahmadian, Jolanda Piepers, Florian Bock, Tom Keulers, Marc A. Vooijs   +5 more
wiley   +1 more source

Short‐term survival of mallards following external transmitter attachment

Ibis, EarlyView.
Capturing birds for external transmitter attachment allows researchers to collect abundant movement and behavioural data across spatial and temporal gradients but can expose birds to additional stress due to prolonged handling, sometimes leading to mortality.
Cassidy L. Waldrep, Madeline A. Ward, John M. Coluccy, Joshua C. Stiller, Jacob N. Straub, Nathaniel R. Huck, Ted. S Barney, Abigail C. Butler, Austin H. Damminger, Shawn W. Meyer, Theodore C. Nichols, Daria J. Sparks, Mathieu Tétreault, Mitch D. Weegman   +13 more
wiley   +1 more source

Proteomic profiling of bull spermatozoa and seminal plasma to inform the rational development of functionally targeted semen extenders for tropical cattle. [PDF]

Vet World
Sahiruddin S, Yusuf M, Diansyah AM, Masturi M, Herdis H, Maulana T, Sihombing VR, Rahmat R, Amrullah MF, Adam AAS, Said S, Alfian AM.   +11 more
europepmc   +1 more source

Endemic but not eroded: Genomic distinctiveness and conservation genomics of the British swallowtail butterfly (Papilio machaon britannicus)

Insect Conservation and Diversity, EarlyView.
Through whole‐genome sequencing of P. machaon populations across Europe, we demonstrate that P. m. britannicus forms a genetically distinct and isolated lineage. Demographic modelling revealed weak historical gene flow from the continent. Although P. m.
Benoit Nabholz, Eliette L. Reboud, Bérénice J. Lafon, Adam M. Cotton, Martin G. Partridge, N. Mark Collins, Fabien L. Condamine   +6 more
wiley   +1 more source