Results 101 to 110 of about 13,148 (179)

Decreased plasma ADAMTS-13 activity as a predictor of postoperative bleeding in cyanotic congenital heart disease

Clinics, 2013
OBJECTIVE: To analyze the preoperative plasma antigenic concentration and activity of von Willebrand factor and its main cleaving protease ADAMTS-13 in pediatric patients with cyanotic congenital heart disease undergoing surgical treatment and ...
Rosangela P.S. Soares, Sérgio P. Bydlowski, Marcelo B. Jatene, Janete Ferreira Hironaka, Antonio Augusto Lopes   +4 more
doaj  

The essential role of calcium in ADAMTS13 function

, 2009
Imperial Users ...
Gardner, Michelle Daniela, Gardner, Michelle Daniela   +1 more
core  

Atypical haemolytic-uraemic syndrome caused by factor H mutation: case report and new management strategies in children [PDF]

, 2012
Atypical haemolytic uraemic syndrome is causedby alternative complement pathway dysregulation. It has recently been recognised that most cases are due to genetic factors and a growing list of mutations has been described.
Araújo, L., Barbot, J., Costa, T., Faria, M., Mota, C., Rocha, L.   +5 more
core  

Investigation of ADAMTS-13 levels in patients with COVID-19 infection

Journal of Infection in Developing Countries
Introduction: Coronavirus disease 2019 (COVID-19) patients are predisposed to thrombotic events. COVID-19 coagulopathy can be associated with ADAMTS-13 (a disintegrin-like and metalloprotease with thrombospondin type I repeats 13) levels. ADAMTS-13, the
Hüseyin H Kutlu, Arzu Sahin, Soycan Mizrak, Abdurrahman Yilmaz, Songul Doganay, Serdar Gungor, Sema Yilmaz   +6 more
doaj   +1 more source

Daratumumab for relapsed refractory immune thrombotic thrombocytopenic purpura: initial response and long-term follow-up

Research and Practice in Thrombosis and Haemostasis
Background: Management of patients with refractory or frequently relapsing (r/r) immune thrombotic thrombocytopenic purpura (iTTP) remains challenging, with no established consensus on optimal therapeutic strategies.
Roman Schimmer, Jana van den Berg, Marissa Schraner, Alice Trinchero, Andreas Holbro, Johanna A. Kremer Hovinga, Jan-Dirk Studt   +6 more
doaj   +1 more source

A Global Assessment of Coagulation Profile and a Novel Insight into Adamts-13 Implication in Neonatal Sepsis. [PDF]

Biology (Basel), 2023
Papadogeorgou P, Boutsikou T, Boutsikou M, Pergantou E, Mantzou A, Papassotiriou I, Iliodromiti Z, Sokou R, Bouza E, Politou M, Iacovidou N, Valsami S.   +11 more
europepmc   +1 more source

Successful Treatment of refractory Thrombotic Thrombocytopenic Purpura With The Monoclonal Antibody Rituximab :A case Report [PDF]

Much of thrombotic thrombocytopenic purpura (TTP) is attributed to the presence of an autoantibody to ADAMTS-13, the metalloprotease that degrades ultralarge von Willebrand protein multimers.
فتحی, افشین, پدرام, محمد   +1 more
core  

A CASE OF THROMBOTIC THROMBOCYTOPENIC PURPURA RELATED TO MALIGNITY AND CHEMOTHERAPY

Hematology, Transfusion and Cell Therapy
Objective: Thrombotic thrombocytopenic purpura (TTP) is a life-threatening multisystem disease. TTP progresses with Microangiopathic hemolytic anemia (MAHA), fever, thrombocytopenia, neurological symptoms, and renal failure.
Ebru Kavak Yavuz, Songül Beskisiz Dönen, Etem Özkaya, Esra Pirinççi, Abdullah Karakuş, Orhan Ayyıldız   +5 more
doaj   +1 more source

Targeting the von Willebrand Factor-ADAMTS-13 axis in sickle cell disease. [PDF]

J Thromb Haemost, 2023
Ellsworth P, Sparkenbaugh EM.
europepmc   +1 more source

Assay for ADAMTS-13 Activity with Flow Cytometric Readout. [PDF]

ACS Omega, 2022
Müller J, Hamedani NS, McRae HL, Rühl H, Oldenburg J, Pötzsch B.   +5 more
europepmc   +1 more source