Results 111 to 120 of about 3,308,144 (197)

Plasma ADAMTS-13 levels and the risk of myocardial infarction: an individual patient data meta-analysis [PDF]

, 2015
Background Low ADAMTS-13 levels have been repeatedly associated with an increased risk of ischemic stroke, but results concerning the risk of myocardial infarction are inconclusive. Objectives To perform an individual patient data meta-analysis from
Lowe, G.D.O., Peyvandi, F., Lowe, GDO, F. R. Rosendaal, D. A. Lane, F. W. Leebeek, Leebeek, Frank, Maino, A., Rosendaal, F.R., Leebeek, FWG, Lane, DA, G. D. Lowe, S. le Cessie, Peyvandi, F, Cessie, S. le, Siegerink, B, Rosendaal, FR, Le Cessie, S, Siegerink, B., le Cessie, S., Lotta, LA, L. A. Lotta, Crawley, JTB, Leebeek, F.W.G., Crawley, J.T.B., Maino, A, A. Maino, J. T. Crawley, B. Siegerink, Lane, D. A., Leebeek, Frank; id_orcid, Lane, D.A., Lotta, L.A., F. Peyvandi   +33 more
core   +1 more source

Decreased plasma ADAMTS-13 activity as a predictor of postoperative bleeding in cyanotic congenital heart disease

Clinics, 2013
OBJECTIVE: To analyze the preoperative plasma antigenic concentration and activity of von Willebrand factor and its main cleaving protease ADAMTS-13 in pediatric patients with cyanotic congenital heart disease undergoing surgical treatment and ...
Rosangela P.S. Soares, Sérgio P. Bydlowski, Marcelo B. Jatene, Janete Ferreira Hironaka, Antonio Augusto Lopes   +4 more
doaj  

Absence of Pro475Ser polymorphism in ADAMTS‐13 in Caucasians [PDF]

Journal of Thrombosis and Haemostasis, 2005
Bongers, TN, de Maat, Moniek, Dippel, Diederik, Uitterlinden, André, Leebeek, Frank   +4 more
openaire   +3 more sources

ADAMTS-13 gene expression in antiphospholipid syndrome Antifosfolipid sendromunda adamts-13 gen ekspresyonu

, 2011
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent thrombosis and fetal mortality. Thrombotic microangiopathy (TMA) is an important histological finding in catastrophic APS (CAPS) and in APS patients with nephropathy. Analysis of familial thrombotic throm-bocytopenic purpura patients showed that there are mutations in ...
TOPAL SARIKAYA, AYŞEGÜL, Hançer, Veysel Sabri, Küçükkaya, Reyhan Diz   +2 more
openaire   +1 more source

The incidence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency

, 2005
Summary. Background: Accurate estimates of the incidence of thrombotic thrombocytopenic purpura (TTP) are important to assess the resources required for current treatments as well as to anticipate the need to develop new treatments.
George, J. N., Vesely, S. K., Terrell, D. R., Williams, L. A., Lämmle, B, Hovinga, J. A. K.   +5 more
core   +1 more source

Investigation of ADAMTS-13 levels in patients with COVID-19 infection

Journal of Infection in Developing Countries
Introduction: Coronavirus disease 2019 (COVID-19) patients are predisposed to thrombotic events. COVID-19 coagulopathy can be associated with ADAMTS-13 (a disintegrin-like and metalloprotease with thrombospondin type I repeats 13) levels. ADAMTS-13, the
Hüseyin H Kutlu, Arzu Sahin, Soycan Mizrak, Abdurrahman Yilmaz, Songul Doganay, Serdar Gungor, Sema Yilmaz   +6 more
doaj   +1 more source

Daratumumab for relapsed refractory immune thrombotic thrombocytopenic purpura: initial response and long-term follow-up

Research and Practice in Thrombosis and Haemostasis
Background: Management of patients with refractory or frequently relapsing (r/r) immune thrombotic thrombocytopenic purpura (iTTP) remains challenging, with no established consensus on optimal therapeutic strategies.
Roman Schimmer, Jana van den Berg, Marissa Schraner, Alice Trinchero, Andreas Holbro, Johanna A. Kremer Hovinga, Jan-Dirk Studt   +6 more
doaj   +1 more source

Reduced ADAMTS-13 level negatively correlates with inflammation factors in plasma of acute myeloid leukemia patients

, 2017
ADAMTS-13 is crucial for maintaining the normal size of vWF. Besides thrombotic thrombocytopenic purpura (TTP), decreased ADAMTS-13 had also been reported in patients with malignancy.
Zhao, Jingzhong, Song, Ying, Wang, Hui, Xu, Qinzhu, Liu, Chen, Zhao, Lei   +5 more
core   +1 more source

Proteolysis of ADAMTS-13 by thrombin does not influence the cleavage of, or binding to, VWF115

, 2011
(A) 5 n ADAMTS-13 or thrombin-cleaved ADAMTS-13 (ADAMTS-13/FIIa) was incubated at 37 °C with 5 μ VWF115, 150 m NaCl, 5 m CaCl, 20 m Tris (pH7.8).
C K N K CHION (48919), S ZANARDELLI (48920), J T B CRAWLEY (48922), J K LAM (48918), D A LANE (48921)   +4 more
core   +1 more source

A Global Assessment of Coagulation Profile and a Novel Insight into Adamts-13 Implication in Neonatal Sepsis. [PDF]

Biology (Basel), 2023
Papadogeorgou P, Boutsikou T, Boutsikou M, Pergantou E, Mantzou A, Papassotiriou I, Iliodromiti Z, Sokou R, Bouza E, Politou M, Iacovidou N, Valsami S.   +11 more
europepmc   +1 more source