Results 91 to 100 of about 4,617,382 (195)
, 2016 (A) Immunohistochemistry shows ADAMTS-1 inside the nucleus of cancer cells (arrows pointed to dot-like structures). Cells under division or stromal-like cells do not present ADAMTS-1 (arrowheads).
Ruy G. Jaeger (618268) +4 more
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Акушерство, гинекология и репродукцияAim: to evaluate a prognostic significance for the vWF/ADAMTS-13 (von Willebrand factor/a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) ratio as an integral biomarker for stratifying the risk of venous thromboembolic events
A. V. Vorobev +10 more
doaj +1 more source
ADAMTS-13, von Willebrand factor and related parameters in severe sepsis and septic shock
, 2007 BACKGROUND: Insufficient control of von Willebrand factor (VWF) multimer size as a result of severely deficient ADAMTS-13 activity results in thrombotic thrombocytopenic purpura associated with microvascluar thrombosis and platelet consumption, features ...
Zeerleder, S +19 more
core +1 more source
Splenectomy in relapsing and plasma-refractory acquired thrombotic thrombocytopenic purpura
Haematologica, 2004 BACKGROUND AND OBJECTIVES: Acquired thrombotic thrombocytopenic purpura (TTP) is often due to autoantibodies inhibiting ADAMTS-13 activity resulting in impaired processing of very large von Willebrand factor multimers.
JA Kremer Hovinga +9 more
doaj
Predictive value of ADAMTS-13 on concealed chronic renal failure in COPD patients
, 2017 Mian Zeng, Qingui Chen, Wenjie Liang, Wanmei He, Haichong Zheng, Chunrong Huang Department of Medical Intensive Care Unit, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China Background: Impaired renal function is often neglected ...
Chen QG +5 more
core
Multi-step binding of ADAMTS-13 to von Willebrand factor
, 2009 Background: ADAMTS-13 proteolytic activity is controlled by the conformation of its substrate, von Willebrand factor (VWF), and changes in the secondary structure of VWF are essential for efficient cleavage.
Anderson, PJ +4 more
core +1 more source
ADAMTS-1 and Aggrecan are both in the nucleus.
, 2016 (A) Colocalization of ADAMTS-1 and aggrecan. ADAMTS-1 (red), Aggrecan (green) and Nuclei (blue). Aggrecan is found in nuclei and cytoplasm and is colocalized with ADAMTS-1 in cell nucleolus (white arrows) in MCF7 and MDA-MB-231. Scale bar: 5 μm.
Ruy G. Jaeger (618268) +4 more
core +1 more source
血浆ADAMTS-13活性和NLR在急性肺血栓栓塞症中的诊断价值
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的探究急性肺血栓栓塞症（PTE）患者血浆血管性血友病因子（vWF）活性、血管性血友病因子裂解酶（ADAMTS-13）活性、中性粒细胞计数与淋巴细胞计数比率（NLR）健康对照组的表达差异，探究ADAMTS-13活性、NLR对于PTE患者的诊断意义。方法共纳入急性PTE患者64例及健康对照者30例，收集相关临床数据并采用酶联免疫吸附试验（ELISA）检测血浆ADAMTS-13活性、vWF活性，分析比较ADAMTS-13活性、vWF活性的组间差异及其与其他临床指标的相关性，绘制受试者工作特征曲线（ROC ...
胡子旋, 何婉媚, 曾勉
doaj
Acquired ADAMTS-13 Deficiency in Pediatric Patients with Severe Sepsis
, 2012 [[abstract]]We studied the state of ultralarge von Willebrand factor (ULVWF) proteolysis in 21 pediatric patients with severe sepsis and found that the overall group of patients had moderately reduced ADAMTS-13 activity, but 31% had severe enzymatic ...
Nguyen, Trung C. ; Liu, Anne; Liu, Li; Ball, Chalmette; Choi, Hiuwan; May, William S. ; Aboulfatova, Khatira; Bergeron, Angela L. ; Dong, Jing-fei
core
Differential expression of ADAMTS -1, -4, -5 and TIMP -3 in rat spinal cord at different stages of acute experimental autoimmune encephalomyelitis [PDF]
, 2005 Experimental autoimmune encephalomyelitis (EAE) is an animal model of inflammatory demyelination, a pathological event common to multiple sclerosis (MS). During CNS inflammation there are alterations in the extracellular matrix (ECM).
Woodroofe, N. +7 more
core +1 more source