Results 91 to 100 of about 13,148 (179)

Acute kidney injury in pregnancy: a clinical challenge [PDF]

, 2012
The incidence of acute kidney injury in pregnancy declined significantly over the second half of the 20th century; however, it is still associated with major maternal and perinatal morbidity and mortality.
Borges, A, Campos, M, Figueiredo, N, Freitas, L, Machado, S, Moura, P, Pais, MS   +6 more
core  

Single Intra‐Articular Anakinra (IL‐1Ra) Versus Betamethasone in Rabbit Post‐Traumatic Knee Osteoarthritis: IL‐8 Suppression and Chondrocyte Viability

Cell Biochemistry and Function, Volume 44, Issue 5, May 2026.
ABSTRACT Post‐traumatic osteoarthritis (OA) is driven by a sustained inflammatory response and progressive osteochondral damage. We compared the effects of a single intra‐articular injection of anakinra (Interleukin‐1 receptor antagonist; IL‐1Ra) with those of betamethasone on structural cartilage outcomes and Interleukin‐8 (IL‐8) immunopositivity in a
Hüseyin Emre Tepedelenlioğlu, Duygu Dayanir, Zübeyir Elmazoğlu, Candan Özoğul, Akif Muhtar Öztürk, Emin Ertuğrul Şener, Çimen Karasu   +6 more
wiley   +1 more source

Role of a Tissue Factor Pathway Inhibitor, the Plasma Proteinase ADAMTS-13 and its Inhibitor in the Pathogenesis of Acute Respiratory Distress Syndrome in A/H1N1 Influenza

Общая реаниматология, 2011
Objective: to study the role of a tissue factor pathway inhibitor (TFPI), the metalloproteinase ADAMTS-13, and its inhibitor in the pathogenesis of acute respiratory distress syndrome (ARDS) in A/H1N1 influenza. Subjects and methods.
E. V. Prutkina, A. V Malyarchikov, N. N. Tsybikov, K. G. Shapovalov, N. V. Isakova   +4 more
doaj   +1 more source

T cell immune abnormalities in immune thrombocytopenia [PDF]

, 2014
Immune thrombocytopenia is an autoimmune disease with abnormal T cell immunity. Cytotoxic T cells, abnormal T regulatory cells, helper T cell imbalance, megakaryocyte maturation abnormalities and abnormal T cell anergy are involved in the pathogenesis of
Jun Peng, Liping Zhang, Ming Hou, Xuebin Ji   +3 more
core   +1 more source

Early Post‑Traumatic Osteoarthritis Features Greater Cartilage Extracellular Matrix Proteoglycan Loss Compared to the Pericellular Matrix

Journal of Orthopaedic Research, Volume 44, Issue 5, May 2026.
ABSTRACT Proteoglycan loss in articular cartilage is a hallmark of post‐traumatic osteoarthritis, and it can affect both chondrocyte biomechanics and tissue health. Previously, we found that 4 weeks after anterior cruciate ligament transection (ACLT) in rabbits, proteoglycan loss was less pronounced in the pericellular matrix (PCM) than in the ...
Rasmus K. Hiltunen, Nina Pesonen, Simo P. Ojanen, Mikko A. J. Finnilä, Sanna Palosaari, Walter Herzog, Simo Saarakkala, Rami K. Korhonen, Juuso T. J. Honkanen, Petri Tanska   +9 more
wiley   +1 more source

ADAMTS13: A New Link Between Thrombosis and Inflammation [PDF]

, 2011
von Willebrand factor (VWF) levels are elevated and a disintegrin-like and metalloprotease with thrombospondin type I repeats–13 (ADAMTS13) activity is decreased in both acute and chronic inflammation.
Brill, Alexander, Chauhan, Anil K., Kisucka, Janka, Scheiflinger, Friedrich, Wagner, Denisa D., Walsh, Meghan T.   +5 more
core   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu, Wenqing Qin, Minghang Dong, Zhi Ma, Si Li, Runping Liu, Ranyun Chen, Changmeng Li, Xiaojiaoyang Li   +8 more
wiley   +1 more source

Regulation of ADAMTS13 by proteolitic enzymes

, 2007
Imperial Users ...
Lam, Jonathan Kai Yan, Lam, Jonathan Kai Yan   +1 more
core  

Behaviour of the von Willebrand Factor in Blood Flow [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Fedosov, DA, Gompper, G, Müller, K   +3 more
core  

The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

Orthopaedic Surgery, Volume 18, Issue 5, Page 897-914, May 2026.
As the key mechanotransducer in IVDD, Piezo1 orchestrates region‐specific degeneration across NP (senescence/ECM dysregulation), AF (apoptosis), and CEP (inflammation). This review integrates mechanistic pathways and assesses multimodal therapeutic targeting (pharmacologic/genetic/nutritional) to restore disc homeostasis.
Guangye Li, Chaoqun Feng, Haoyun Huang, Junwen Deng, Fei Yang, Rigao Chen   +5 more
wiley   +1 more source