Results 141 to 150 of about 11,934 (162)

Screening, isolation and characterisation of antibodies that block aggrecanase activity of ADAMTS-5

2013
A Disintegrin and Metalloproteinase with ThromboSpondin Motif (ADAMTS)-5 is considered to play a key role in degradation of aggrecan during the progression of osteoarthritis (OA). Thus, ADAMTS-5 inhibitors are emerging as potential disease-modifying OA drugs.
openaire   +2 more sources

Hypoxic regulation of ADAMTS-2 and -3 (a disintegrin and matrix metalloproteinase with thrombospondin motifs 2 and 3) procollagen N proteinases by HIF-1α in endothelial cells

Molecular and Cellular Biochemistry, 2022
Meltem Alper, Candan Altuntas, Feray Köçkar   +2 more
exaly  

Role of ADAMTS-1 in Atherosclerosis

Arteriosclerosis, Thrombosis, and Vascular Biology, 2005
Peter Brodin, Birgitta Rosengren
exaly  

Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation

Rheumatology International, 2008
Kelvin S C Cheung, Ko Hashimoto, Helmtrud I Roach   +2 more
exaly  

Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin

Osteoarthritis and Cartilage, 2008
Mary B Goldring, S B Abramson, P E di Cesare   +2 more
exaly  

An open conformation of ADAMTS-13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura

Journal of Thrombosis and Haemostasis, 2018
Andreas Greinacher, Karen Vanhoorelbeke, Hans Deckmyn   +2 more
exaly  

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics

Matrix Biology, 2015
Suneel S Apte, Johanne Dubail
exaly  

ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage

Matrix Biology, 2004
Edward R Lavallie, Elisabeth A Morris, Lisa A Collins-Racie   +2 more
exaly  

Human endothelial cells synthesize and release ADAMTS-13

Journal of Thrombosis and Haemostasis, 2006
J -F Dong, J-F Dong, N Turner
exaly  

IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc

Journal of Orthopaedic Surgery and Research, 2015
Chao Liu, Zhongyi Sun, He Liang
exaly