Results 111 to 120 of about 13,808 (210)

Increased expression of ADAMTS13 mRNA correlates with ischemic cerebrovascular disease in systemic lupus erythematosus patients

SAGE Open Medicine, 2013
Objective: We investigated ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type 1 motif, member 13) messenger RNA levels as a biomarker of disease features in systemic lupus erythematosus.
Consuelo M López De Padilla, Molly S Hein, Cynthia S Crowson, Christopher S Choo, Abigail B Green, Michelle Petri, Hatice Bilgic, Emily C Baechler, Ann M Reed   +8 more
doaj   +1 more source

The first deletion mutation in the TSP1-6 repeat domain of ADAMTS13 in a family with inherited thrombotic thrombocytopenic purpura

Haematologica, 2009
The inherited deficiency of ADAMTS13 is usually associated with severe forms of thrombotic thrombocytopenic purpura. Among the mutations identified in the ADAMTS13 gene, none have been described on the TSP1-6 repeat domain.
Roberta Palla, Silvia Lavoretano, Rossana Lombardi, Isabella Garagiola, Mehran Karimi, Abdolreza Afrasiabi, Mani Ramzi, Raimondo De Cristofaro, Flora Peyvandi   +8 more
doaj   +1 more source

Multi-lectin Affinity Chromatography and Quantitative Proteomic Analysis Reveal Differential Glycoform Levels between Prostate Cancer and Benign Prostatic Hyperplasia Sera. [PDF]

, 2018
Currently prostate-specific antigen is used for prostate cancer (PCa) screening, however it lacks the necessary specificity for differentiating PCa from other diseases of the prostate such as benign prostatic hyperplasia (BPH), presenting a clinical need
Adusumilli, Ravali, Brooks, James D, Kullolli, Majlinda, Mallick, Parag, Pitteri, Sharon J, Tanimoto, Cheylene, Totten, Sarah M   +6 more
core   +2 more sources

Pilot study of ADAMTS13 activity and anti-ADAMTS13 antibodies stability

Hämostaseologie
Introduction Thrombotic thrombocytopenic purpura (TTP) is a rare disease characterized by thrombocytopenia, microangiopathic hemolytic anemia, neurological disorders, renal dysfunction and febrility. TTP occurs due to ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 13) deficiency, which is most often a consequence of
A. Bogić, D. Coen Herak, M. Miloš, D. Rogić   +3 more
openaire   +1 more source

Autoantibody-resistant ADAMTS13 variant [PDF]

Blood, 2021
openaire   +2 more sources

Vitamin B12 Deficiency with Pseudothrombotic Microangiopathy and Thrombotic Thrombocytopenic Purpura: Similarities and Differences [PDF]

, 2020
Buess, Charles, Germann, Alexander, Maloney, Eamon, Mohammed, Alaeldin   +3 more
core   +2 more sources

The essential role of calcium in ADAMTS13 function

, 2009
Imperial Users ...
Gardner, Michelle Daniela, Gardner, Michelle Daniela   +1 more
core  

GC1126A, a novel ADAMTS13 mutein, evades autoantibodies in immune-mediated thrombotic thrombocytopenic purpura

Scientific Reports
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare and life-threatening blood disorder characterized by the formation of blood clots in small blood vessels. It is caused by antibodies targeting the A disintegrin and metalloprotease with
Heechun Kwak, Gahee Choi, Suyong Kim, Ji-Min Park, Youngeun Kwon, Yongmin Lee, Chaemok Lee, Shangbin Yang, Spero Cataland, Sunghyun Kim, Soo-Mee Bang, Jae-Ho Yoon, Wooin Lee, Hyun-Ja Nam   +13 more
doaj   +1 more source

Anti-ADAMTS13 Autoantibodies in Immune-Mediated Thrombotic Thrombocytopenic Purpura

Antibodies
Autoantibodies to ADAMTS13 are at the center of pathology of the immune-mediated thrombotic thrombocytopenic purpura. These autoantibodies can be either inhibitory (enzymatic function) or non-inhibitory, resulting in protein depletion.
Michael R. Snyder, Robert W. Maitta
doaj   +1 more source

Regulation of ADAMTS13 by proteolitic enzymes

, 2007
Imperial Users ...
Lam, Jonathan Kai Yan, Lam, Jonathan Kai Yan   +1 more
core