Results 51 to 60 of about 8,376 (205)
Thrombotic microangiopathies: thrombotic thrombocytopenic purpura / hemolytic uremic syndrome [PDF]
, 2010 Thrombotic microangiopathies (TMAs) are pathological conditions characterized by generalized microvascular occlusion by platelet thrombi, thrombocytopenia, and microangiopathic hemolytic anemia.
Mastroianni Kirsztajn, Gianna +1 more
core +2 more sources
Shedding Light on the Possible Link between ADAMTS13 and Vaccine—Induced Thrombotic Thrombocytopenia
Cells, 2021 Several recent reports have highlighted the onset of vaccine-induced thrombotic thrombocytopaenia (VITT) in some recipients (approximately 1 case out of 100k exposures) of the ChAdOx1 nCoV-19 vaccine (AstraZeneca).
Anna Szóstek-Mioduchowska +1 more
doaj +1 more source
Thrombotic microangiopathy and associated renal disorders [PDF]
, 2012 Thrombotic microangiopathy (TMA) is a pathological process involving thrombocytopenia, microangiopathic haemolytic anaemia and microvascular occlusion.
Barbour, T +3 more
core +1 more source
Molecules, 2021 In recent years, sea cucumber has become a favorite healthcare food due to its characteristic prevention of cardiovascular diseases, suppression of tumors, as well as enhancement of immunity.
Rong Qiao +7 more
doaj +1 more source
Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK [PDF]
, 2018 Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased
Cardwell, J M +5 more
core +1 more source
Intracranial aneurysm’s association with genetic variants, transcription abnormality, and methylation changes in ADAMTS genes [PDF]
PeerJ, 2020 Purpose The development of intracranial aneurysm (IA) has been linked to genetic factors. The current study examines the potential role of genes encoding disintegrin and metalloproteinase using thrombospondin motifs (ADAMTS) in IA development.
Shi Chen +8 more
doaj +2 more sources
Soluble C5b‐9 (sC5b‐9) in Pediatrics—A Clinical Assessment
Journal of Clinical Laboratory Analysis, EarlyView.The sc5b9 assay is a simple laboratory‐developed test that can be used in specific patients to monitor the course of disease, severity, or response to therapy. Future studies using this assay, which show excellent adaptability to a clinical laboratory, will reveal the multiple uses of testing for complement activation.
Ridwan B. Ibrahim +3 more
wiley +1 more source
Journal for ImmunoTherapy of Cancer, 2023 Background An increased incidence of thrombotic complications associated with an increased mortality rate has been observed under immune checkpoint inhibition (ICI).
Stefan W Schneider +18 more
doaj +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, life‐threatening thrombotic microangiopathy caused by a severe inherited deficiency of ADAMTS13, a von Willebrand factor (VWF) cleaving enzyme. Inadequate clinical endpoint data often make it challenging to statistically power clinical trials in ultra‐rare diseases ...
Cameron McBride +8 more
wiley +1 more source
A case of refractory thrombotic thrombocytopenic purpura treated with plasmapheresis and rituximab [PDF]
, 2016 Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder with no prevalence or incidence studies in sub-Saharan Africa. Acquired TTP has several causes, all of which lead to decreased activity of von Willebrand factor cleaving ...
Kirui, Nicholas, Sokwala, Ahmed
core +4 more sources