Results 31 to 40 of about 2,929,035 (154)

ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1) [PDF]

, 2009
Review on ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1), with data on DNA, on the protein encoded, and where the gene is ...
Rocks, N, Cataldo, D
core   +1 more source

Gene expression profiling of upregulated mRNAs in granulosa cells of bovine ovulatory follicles following stimulation with hCG

Reproductive Biology and Endocrinology, 2017
Background Ovulation and luteinization of follicles are complex biological processes initiated by the preovulatory luteinizing hormone surge. The objective of this study was to identify genes that are differentially expressed in bovine granulosa cells ...
Jacques G. Lussier, Mame N. Diouf, Valérie Lévesque, Jean Sirois, Kalidou Ndiaye   +4 more
doaj   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

Remote ischemic preconditioning attenuates intestinal mucosal damage: insight from a rat model of ischemia–reperfusion injury

Journal of Translational Medicine, 2019
Background Remote ischemic preconditioning (RIPC) is a phenomenon, whereby repeated, non-lethal episodes of ischemia to an organ or limb exert protection against ischemia–reperfusion (I/R) injury in distant organs.
Lars Hummitzsch, Karina Zitta, Rouven Berndt, Yuk Lung Wong, Rene Rusch, Katharina Hess, Thilo Wedel, Matthias Gruenewald, Jochen Cremer, Markus Steinfath, Martin Albrecht   +10 more
doaj   +1 more source

Expression of ADAMTS1 in endothelial cells is induced by shear stress and suppressed in sprouting capillaries

, 2010
ADAMTS1 inhibits capillary sprouting, and since capillary sprouts do not experience the shear stress caused by blood flow, this study undertook to clarify the relationship between shear stress and ADAMTS1.
Hoffmann, Christian J, Mauro Bongrazio, Beata Styp-Rekowska, Wunderlich, Wulf, Knudsen, Rose, Fiedorowicz, Katarzyna, Maroski, Julian, Sven Chlench, Vorderwülbecke, Bernd J, Lehmann, Robert, Michael Hoepfner, Bernd J. Vorderwülbecke, Axel R. Pries, Robert Lehmann, Luis Da Silva-Azevedo, Pries, Axel R, Chlench, Sven, Katarzyna Fiedorowicz, Hohberg, Margret, Christian J. Hoffmann, Knöchel, Judith, Rose Knudsen, Da Silva-Azevedo, Luis, Judith Knöchel, Julian Maroski, Bongrazio, Mauro, Alexander Alter, Alter, Alexander, Zakrzewicz, Andreas, Margret Hohberg, Nitsche, Bianca, Styp-Rekowska, Beata, Wulf Wunderlich, Hoepfner, Michael, Bianca Nitsche, Andreas Zakrzewicz   +35 more
core   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

Increased protein expression of ADAMTS1 and -4 after aortic banding.

, 2014
Myocardial protein expression of ADAMTS1 (A) and -4 (B) in rats with preserved (HFpFS, n = 9) or reduced FS (HFrFS, n = 6) six weeks after aortic banding.
Jan Magnus Aronsen (347485), Ivar Sjaastad (162165), Cathrine R. Carlson (193912), Ida G. Lunde (193866), Geir Christensen (162197), Maria Vistnes (529698)   +5 more
core   +1 more source

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, EarlyView.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

Control of cytokine mRNA degradation by the histone deacetylase inhibitor ITF2357 in rheumatoid arthritis fibroblast-like synoviocytes: beyond transcriptional regulation

Arthritis Research & Therapy, 2018
Background Histone deacetylase inhibitors (HDACi) suppress cytokine production in immune and stromal cells of patients with rheumatoid arthritis (RA).
Chiara Angiolilli, Pawel A. Kabala, Aleksander M. Grabiec, Marzia Rossato, Wi S. Lai, Gianluca Fossati, Paolo Mascagni, Christian Steinkühler, Perry J. Blackshear, Kris A. Reedquist, Dominique L. Baeten, Timothy R. D. J. Radstake   +11 more
doaj   +1 more source