Results 51 to 60 of about 15,574 (255)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Adaptively profiling models with task elicitation

Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing
Language model evaluations often fail to characterize consequential failure modes, forcing experts to inspect outputs and build new benchmarks. We introduce task elicitation, a method that automatically builds new evaluations to profile model behavior.
Davis Brown, Prithvi Balehannina, Helen Jin, Shreya Havaldar, Hamed Hassani, Eric Wong 0001   +5 more
openaire   +2 more sources

Maturational differences in physical self-perceptions and the relationship with physical activity in early adolescent girls [PDF]

, 2007
This cross-sectional study examined the effect of physical self-perceptions and maturation on physical activity, and considered the influence of maturation and age on physical self-perceptions in early adolescent girls (n = 208; mean age = 11.83 ± 0.39 ...
Niven, Ailsa, Knowles, Ann Marie, Knowles, Ann-Marie, Fawkner, Samantha G., Fawkner, Samantha, Niven, Ailsa G., Stephenson, Claire   +6 more
core  

Validation of wastewater data using artificial intelligence tools and the evaluation of their performance regarding annotator agreement

Water Science and Technology, 2023
To prevent the pollution of water resources, the measurement and the limitation of wastewater discharges are required. Despite the progress in the field of data acquisition systems, sensors are subject to malfunctions that can bias the evaluation of the ...
Imane Zidaoui, Cédric Wemmert, Matthieu Dufresne, Claude Joannis, Sandra Isel, Jonathan Wertel, José Vazquez   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Modelling vertical concentration distributions of solids suspended in turbulent visco-plastic fluid

Journal of Hydrology and Hydromechanics, 2021
Vertical concentration distributions of solids conveyed in Newtonian fluids can be modelled using Rouse-Schmidt type distributions. Observations of solids conveyed in turbulent low Reynolds number visco-plastic carriers, suggest that solids are more ...
Matoušek Václav, Chryss Andrew, Pullum Lionel   +2 more
doaj   +1 more source

Implications of Lifestyle Factors and Polygenic Risk Score for Absolute Risk Prediction of Colorectal Neoplasm and Risk-Adapted Screening

Frontiers in Molecular Biosciences, 2021
Background: Estimation of absolute risk of developing colorectal neoplasm is essential for personalized colorectal cancer (CRC) screening. We developed models to determine relative and absolute risks of colorectal neoplasm based on lifestyle and genetic ...
Hongda Chen, Li Liu, Ming Lu, Yuhan Zhang, Bin Lu, Ying Zhu, Jianbo Tian, Xinying Li, Shaofa Nie, Xiaoping Miao, Min Dai   +10 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Successful Anatomy Adapted Therapeutic Management and Genetic Profiling of Primary Pituitary Diffuse Large B-Cell Lymphoma

, 2023
ErinMarie O Kimbrough,1 Vivek Gupta,2 Liuyan Jiang,3 Han W Tun1 1Division of Hematology and Oncology, Mayo Clinic, Jacksonville, FL, USA; 2Department of Radiology, Mayo Clinic, Jacksonville, FL, USA; 3Department of Pathology, Mayo Clinic, Jacksonville ...
Jiang L, Gupta V, Kimbrough EO, Tun HW
core  

GAS THRUST BEARING OF INCREASED BEARING CAPACITY WITH YIELDING BEARING SURFACE

Вестник Донского государственного технического университета, 2018
Basic operation factors of the deformed gas-lubricated thrust bearing with increased bearing capacity are theoretically analysed. It is shown that steady-state operation characteristics of this bearing differ from those of the rigid bearing.
Kamil S. AKHVERDIYEV, Murman A. MUKUTADZE, Vladimir A. KONSTANTINOV   +2 more
doaj