Results 91 to 100 of about 809,797 (292)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Temporal convex combination‐based secure distributed estimation against cyberattacks and noisy input

open access: yesElectronics Letters
This paper proposes a new secure distributed estimation for cyber‐physical systems against adversarial attacks with noisy input. To mitigate the effect of attacks, a novel distributed attack detection based on a reliable reference estimation obtained by ...
Zhanxi Zhang   +4 more
doaj   +1 more source

Bayesian Signal Recovery Under Measurement Matrix Uncertainty: Performance Analysis

open access: yesIEEE Access, 2019
Compressive sensing (CS) has gained a lot of attention in recent years due to its benefits in saving measurement time and storage cost in many applications including biomedical imaging, wireless communications, image reconstruction, remote sensing, and ...
Abolfazl Razi
doaj   +1 more source

Adaptive Bayesian Estimation of Conditional Densities

open access: yes, 2016
We consider a non-parametric Bayesian model for conditional densities. The model is a finite mixture of normal distributions with covariate dependent multinomial logit mixing probabilities.
Norets, Andriy, Pati, Debdeep
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Target Tracking Using a Time-Varying Autoregressive Dynamic Model

open access: yesIEEE Open Journal of Signal Processing
Target tracking algorithms commonly use structured dynamic models which require prior training of fixed model parameters. These trackers have reduced accuracy if the target behaviour does not match the dynamic model.
Ralph J. Mcdougall, Simon J. Godsill
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Deformable cardiac surface tracking by adaptive estimation algorithms. [PDF]

open access: yesSci Rep, 2023
Tuna EE   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Estimation of aircraft distances using transponder signal strength information

open access: yesCogent Engineering, 2018
The Federal Aviation Administration has recently mandated the installation of transponders that provide position reporting (Extended Mode S) in aircraft operating in most types of domestic controlled airspace by January 1, 2020.
John H. Mott
doaj   +1 more source

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