Results 241 to 250 of about 312,631 (303)

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

Advanced Healthcare Materials, EarlyView.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim, Ji Seob Kim, Min Hee Moon, Jae‐Hyeok Jang, In Sun Hwang, Byung‐Hyun Cha   +5 more
wiley   +1 more source

Synergistic innate-adaptive immunity by NKG2D-specific CAR-macrophages drives durable remission in hepatocellular carcinoma. [PDF]

Mol Cancer
Zhao Z, Zheng W, He Y, Zhang H, Zhang L, Huo Y, Jiang J, Zhang C, Lyu H, Qin W, Liu C, Chang F, Shan L, Wang T, Song W.   +14 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Immune organoids: emerging platforms for modeling and analyzing human adaptive immunity. [PDF]

Front Immunol
Li T, Peng D, Yao M, Li M, Wang Y, Li S, Zhang D, Yang B, Qiu HJ, Li LF.   +9 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Trained ILCs confer adaptive immunity-independent protection against influenza. [PDF]

J Virol
Mboko WP, Wang Y, Cao W, Sayedahmed EE, Mishina M, Kumar A, Bohannon CD, Patton SK, Ray SD, Sharma SD, Kumari R, Liepkalns JS, Reber AJ, Kamal RP, McCoy J, Amoah S, Ranjan P, Burroughs M, Sheth M, Lee J, Batra D, Gangappa S, York IA, Knight PR, Pohl J, Mittal SK, Sambhara S.   +26 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Histocompatibility in Botryllus schlosseri and the origins of adaptive immunity. [PDF]

Immunogenetics
De Tomaso AW, Rodriguez-Valbuena H.
europepmc   +1 more source

Innate and adaptive immunity in neurodegenerative disease. [PDF]

Cell Mol Life Sci
Huang Y, Zhang G, Li S, Feng J, Zhang Z.
europepmc   +1 more source