Expanding the use of real-time electromagnetic tracking in radiation oncology. [PDF]
, 2011 In the past 10 years, techniques to improve radiotherapy delivery, such as intensity-modulated radiation therapy (IMRT), image-guided radiation therapy (IGRT) for both inter- and intrafraction tumor localization, and hypofractionated delivery techniques ...
Kupelian, Patrick A +3 more
core +1 more source
"Dose of the day" based on cone beam computed tomography and deformable image registration for lung cancer radiotherapy. [PDF]
, 2020 PURPOSE:Adaptive radiotherapy (ART) has potential to reduce toxicity and facilitate safe dose escalation. Dose calculations with the planning CT deformed to cone beam CT (CBCT) have shown promise for estimating the "dose of the day".
Benedict, Stanley H +5 more
core +1 more source
Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]
, 2014 It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R. +3 more
core +3 more sources
A survey of practice patterns for adaptive particle therapy for interfractional changes
Physics and Imaging in Radiation Oncology, 2023 Background and purpose: Anatomical changes may compromise the planned target coverage and organs-at-risk dose in particle therapy. This study reports on the practice patterns for adaptive particle therapy (APT) to evaluate current clinical practice and ...
Petra Trnkova +10 more
doaj +1 more source
Cone-Beam Computed Tomography and Deformable Registration-Based “Dose of the Day” Calculations for Adaptive Proton Therapy [PDF]
, 2015 Purpose: The aim of this work was to evaluate the feasibility of cone-beam computed tomography (CBCT) and deformable image registration (DIR)–based ‘‘dose of the day’’ calculations for adaptive proton therapy.
Alshaikhi, J +7 more
core +1 more source
Sensitivity analysis of Monte Carlo model of a gantry-mounted passively scattered proton system [PDF]
, 2020 PURPOSE: This study aimed to present guidance on the correlation between treatment nozzle and proton source parameters, and dose distribution of a passive double scattering compact proton therapy unit, known as Mevion S250.
Baradaran-Ghahfarokhi, Milad +4 more
core +2 more sources
Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes. [PDF]
, 2016 Low-dose antithymocyte globulin (ATG) plus pegylated granulocyte colony-stimulating factor (G-CSF) preserves β-cell function for at least 12 months in type 1 diabetes.
Atkinson, Mark A +14 more
core +3 more sources
Spot Weight Adaptation for Moving Target in Spot Scanning Proton Therapy [PDF]
Frontiers in Oncology, 2015 This study describes a real-time spot weight adaptation method in spot-scanning proton therapy for moving target or moving patient, so that the resultant dose distribution closely matches the planned dose distribution.The method proposed in this study adapts the weight (MU) of the delivering pencil beam to that of the target spot; it will actually hit ...
Paul eMorel +7 more
openaire +4 more sources
, 2019 Purpose: CBCT-based adaptive radiotherapy requires daily images for accurate dose calculations. This study investigates the feasibility of applying a single convolutional network to facilitate CBCT-to-CT synthesis for head-and-neck, lung, and breast ...
Berg, Cornelis AT van den +6 more
core +1 more source
Physics and Imaging in Radiation Oncology, 2023 The potential of proton therapy is currently limited due to large safety margins. We estimated the potential reduction of clinical margins when using prompt gamma imaging (PGI) for online treatment verification of prostate cancer.
Stefanie Bertschi +6 more
doaj +1 more source