Results 41 to 50 of about 4,080,669 (137)

Beyond Photons: Emerging Advances and Clinical Potential of Proton Beam Therapy in Gynecological Malignancies

Radiation
Radiation therapy is central to the management of gynecological cancers, including endometrial, cervical, ovarian, and vaginal malignancies. Despite advances in photon-based techniques, treatment-related toxicity remains significant owing to the ...
Lifeng Chen, Li Wang, Hamid A. Bakshi
doaj   +1 more source

Comprehensive quality control process for high precision intensity modulated adaptive proton therapy [PDF]

, 2021
The thesis focuses on development and clinical implementation of comprehensive and overlaying quality control process aimed at supporting introduction of high precision adaptive IMPT workflows.
Meijers, Artürs; id_orcid, null null, Artürs Meijers   +2 more
core   +1 more source

Innovative radiotherapy approaches

ESMO Gastrointestinal Oncology
Radiotherapy (RT) with concurrent chemotherapy is the standard of care for squamous-cell carcinoma of the anal canal (SCCAC), achieving favorable results in terms of local control and overall survival. However, locoregional failure remains common despite
G. Chiloiro, P. Franco, M.P. Nilsson, A. Romano, E. Serup-Hansen, B. Fionda, S. Manfrida, C. Kronborg, M.A. Gambacorta   +8 more
doaj   +1 more source

Monte Carlo study of secondary electron production from gold nanoparticle in proton beam irradiation [PDF]

, 2014
Purpose: In this study, we examined some characteristics of secondary electrons produced by gold nanoparticle (NP) during proton beam irradiation.Method: By using the Geant4 Monte Carlo simulation toolkit, we simulated the NP at the range from radius (r)
Gao, Jeff; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, Oklahoma, Zheng, Yuanshui; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, Oklahoma   +1 more
core   +3 more sources

Comparing Predicted Toxicities between Hypofractionated Proton and Photon Radiotherapy of Liver Cancer Patients with Different Adaptive Schemes

, 2023
With the availability of MRI linacs, online adaptive intensity modulated radiotherapy (IMRT) has become a treatment option for liver cancer patients, often combined with hypofractionation.
Lena Nenoff, Jennifer Pursley, Gregory C. Sharp, Harald Paganetti, Jackson Lau, Atchar Sudhyadhom   +5 more
core   +1 more source

Proton accelerators

, 2012
Until the 1990s proton therapy was performed in nuclear physics laboratories that were equipped with a particle accelerator. Typically an (isochronous) cyclotron or a synchrocyclotron was available, and in most cases the medical program had to compete ...
Schippers, Marco (author)
core   +1 more source

Proton Therapy in the Management of Hepatocellular Carcinoma [PDF]

, 2022
SIMPLE SUMMARY: Radiation therapy is among the locoregional therapy modalities used to treat unresectable or medically inoperable hepatocellular carcinoma (HCC).
Hilal, Lara, Kobeissi, Jana M., Charles B. Simone, Jana M. Kobeissi, Haibo Lin, Carla Hajj, Lin, Haibo, Christopher H. Crane, Simone, Charles B., Lara Hilal, Crane, Christopher H., Hajj, Carla   +11 more
core   +1 more source

Fast Monte Carlo dose calculation in proton therapy. [PDF]

This article examines the critical role of fast Monte Carlo dose calculations in advancing proton therapy techniques, particularly in the context of increasing treatment customization and precision.
Zhang, Lian, Holmes, Jason, Fix, Michael K, Liu, Wei, Jiang, Steve B, Feng, Hongying   +5 more
core   +2 more sources

Impact of reduced robustness settings on the necessity for proton therapy treatment plan adaptation in head-and-neck cancer patients

Physics and Imaging in Radiation Oncology
Background and purpose: Robust optimization mitigates the effects of range and setup uncertainties in intensity–modulated proton therapy (IMPT) through robustness settings. However, it increases the dose to organs-at-risk (OARs).
Brian Zapien-Campos, Dirk Wagenaar, Tim Franssen, Hans Verbeek, Stefan Both, Peter Dendooven   +5 more
doaj   +1 more source

Comparison of gantry-less magnetic resonance guided proton therapy with photon therapy for hepatocellular carcinoma patients

Physics and Imaging in Radiation Oncology
Background and purpose: With magnetic resonance imaging (MRI), soft-tissue tumors such as hepatocellular carcinoma (HCC) are visualised. MR guided proton therapy (MRgPT) may combine the advantages of proton therapy with soft-tissue image-guidance ...
Franciska Lebbink, Emilie Alvarez Michael, Anna Kornek, Annika Lattermann, Chiara Valentini, Petra Trnkova, Esther G.C. Troost   +6 more
doaj   +1 more source